MSAT Technical Lead – Drug Substance, Senior Manager

🕒 Junho 25

🔔 Pennsylvania – Remoto

🔔 Pennsylvania – Remote

💵 $140.000 - $165.000 / ano

⏰ Tempo Integral

🟠 Sênior

🧑‍💻 Engenheiro Full-stack

Candidatar-se

Encontrar Vagas Remotas Similares

Configurar Alerta de Email para Novas Vagas

📊 Verifique sua pontuação de currículo para esta vaga

Melhore suas chances de conseguir uma entrevista verificando sua pontuação de currículo antes de se candidatar.

Enviar Currículo

Sobi - Swedish Orphan Biovitrum AB (publ)

SiteLinkedInTodas as Vagas

1001 - 5000 funcionários

Fundada em 1991

🏥 Saúde

🧬 Biotecnologia

💊 Farmacêutico

Healthcare • Biotechnology • Pharmaceuticals

A Sobi é uma empresa biofarmacêutica internacional especializada em transformar a vida de pessoas com doenças raras. Oferecemos acesso sustentável a terapias inovadoras nas áreas de hematologia, imunologia e indicações especiais. Atualmente, empregamos aproximadamente 1.600 pessoas na Europa, América do Norte, Oriente Médio e Ásia. Em 2021, nosso faturamento foi de SEK 15,5 bilhões. As ações da Sobi (STO:SOBI) estão listadas na Nasdaq de Estocolmo. Você pode encontrar mais informações sobre a Sobi em sobi.com. Leia nossa política de mídias sociais em https://www.sobi.com/en/social-media-policy Você pode saber mais sobre a Sobi em https://www.youtube.com/c/sobipharma

Descrição

• Subject matter expert (SME) for Small Molecules Drug Substance Manufacturing. • Process owner of Small Molecules process validation for Sobi products. • Lead and execute MSAT projects such as manufacturing process and cost improvement as part of LCM. • Participate in internal activities related to (external) manufacturing, such as process changes, major/critical deviations, risk assessments, and CAPAs. • Issue, review, and approve applicable internal and external SOP’s and manufacturing instructions. • Review and supervise the setup, execution, and documentation of technical studies, qualifications, and validations. • Write and review applicable sections of the APR/PQR. • Write and review applicable sections in registration files, variations, and market expansion. • Support in sourcing evaluation of new Small Molecules contract manufacturers and participation in developing supply and quality agreements. • Lead the technical part of a product transfer, scale-up activities, validations, and oversee manufacturing of Small Molecules processes at external manufacturers for Sobi projects in the clinical and commercial phase. • Be aware of external biopharmaceutical manufacturing technology advancements, understand and introduce new technologies, and how they may be applicable to process innovation, cost, or yield improvement.

🎯 Requisitos

• University degree in Chemistry, Biology, Biotechnology, Pharmacy, or similar • 6+ years of experience in the development and manufacturing of small-molecule drug substances for clinical and commercial use • 3+ years of experience in a commercial setting, leading the technical pieces of product transfer, scale-up, and validation • Experience reviewing applicable sections of the APR/PQR • Scientific and technical background in CMC development and manufacturing of drug substances, small molecules • Experience with regulatory guidelines, regulatory authorities communication, and file documentation • Experience overseeing external vendors such as CMOs, CDMOs, etc. • Demonstrable experience working in a cross-functional team with the ability to multitask, prioritize, and be an effective decision-maker.

🏖️ Benefícios

• A competitive 401(k) match to support your financial future. • Tuition and wellness reimbursements to invest in your personal and professional growth. • A comprehensive medical, dental, and vision package to prioritize your health and well-being. • Additional recognition awards to celebrate your achievements.