Scientist, Cell Therapy

🕒 April 23

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Parexel

WebsiteLinkedInAll Job Openings

10,000+ employees

Founded 1983

⚕️ Healthcare Insurance

🧬 Biotechnology

💊 Pharmaceuticals

💰 Venture Round on 1990-01

Healthcare Insurance • Biotechnology • Pharmaceuticals

Parexel is one of the world's largest clinical research organizations (CROs), providing comprehensive services for the clinical development process from Phase I to IV. The company specializes in portfolio management, clinical trial management, regulatory strategy, market access, and lifecycle management for biopharmaceuticals. Parexel aims to speed life-changing medicines to market by leveraging its clinical, regulatory, and therapeutic expertise. With a global team of over 21,000 professionals, Parexel works to integrate patient insights and innovative trial designs to develop treatments across therapeutic areas such as oncology, neuroscience, rare diseases, and more. It focuses on delivering patient-centric and efficient clinical trials.

📋 Description

• Own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization • Partner with project teams to enable data-driven decisions that advance programs from discovery toward translation • Help shape study plans, and ensure timely delivery of milestones across functions • Design and run in vitro studies for CAR T candidates; design constructs and characterize engineered cell therapies; develop, execute, and optimize functional assays • Analyze data, generate figures, and prepare reports and slide decks, present results and propose next experiment steps • Ensure adherence to required training and maintain accurate, complete experimental records • Align with Pharmacology & Toxicology, CMC, translational science and clinical teams to advance project • Clear scientific writing and presentation, mentor colleagues and foster a productive, well-organized lab environment • Track record of trouble shooting models, optimizing protocols, and meeting timelines in a dynamic environment

🎯 Requirements

• PhD in immunology, cell biology, or related field; or MS with 4+ years demonstrated impact in cell therapy discovery • Proficient in human primary cell isolation, culture, activation, and maintenance • Prepare lentiviral vectors and perform transduction; optimize MOI to maximize transduction efficiency; assess vector copy number and integration characteristics; conduct electroporation-based gene edits • Proficient in panel design, compensation, and gating • Functional assays: target killing (luciferase/impedance), cytokines, proliferation/persistence, serial-kill or rechallenge assays; antigen density titration and specificity testing • PCR/qPCR, plasmid prep; amplicon NGS prep for edit verification and transgene integrity • Proficiency with ELN, FlowJo, Snapgene, GraphPad; understanding of assay acceptance criteria and basic statistics • Practice BSL 2 biosafety, uphold animal ethics (IACUC), maintain awareness of research GxP, and ensure data integrity

🏖️ Benefits

• Health insurance • Professional development