
11 - 50 employés
🧬 Biotechnologie
🤖 Intelligence artificielle
🏥 Santé
Biotechnology • Artificial Intelligence • Healthcare
Peptone est une société pionnière de biophysique translationnelle préclinique, dédiée à la découverte de nouveaux traitements ciblant les protéines intrinsèquement désordonnées. En s’appuyant sur une intelligence artificielle avancée et le calcul haute performance, Peptone ambitionne de mettre de l’ordre dans les complexités biologiques associées à ces protéines désordonnées afin de révolutionner potentiellement les approches thérapeutiques en biotechnologie.
🕒 il y a 12 jours
🗣️🇺🇸🇬🇧 Anglais requis
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11 - 50 employés
🧬 Biotechnologie
🤖 Intelligence artificielle
🏥 Santé
Biotechnology • Artificial Intelligence • Healthcare
Peptone est une société pionnière de biophysique translationnelle préclinique, dédiée à la découverte de nouveaux traitements ciblant les protéines intrinsèquement désordonnées. En s’appuyant sur une intelligence artificielle avancée et le calcul haute performance, Peptone ambitionne de mettre de l’ordre dans les complexités biologiques associées à ces protéines désordonnées afin de révolutionner potentiellement les approches thérapeutiques en biotechnologie.
• Support medicinal chemistry projects and coordinate synthetic chemistry activities to deliver high-quality small molecule development candidates within competitive timeframes • Safeguard the Company’s intellectual property by advancing its patent estate • Support management of remote teams of medicinal and synthetic chemists at CROs • Integrate and analyse project biology and DMPK data for hit-to-lead and lead optimisation campaigns through rational molecular design • Upload project data to the company database and record it in the ELN • Support patent filings with experimental write-up and data checking • Collaborate with project teams, biology, biophysics, computational sciences colleagues, and external collaborators • Communicate effectively and interpret and summarise complex data for different audiences • Prioritise work according to project goals and ensure timely delivery of objectives • Keep current with state-of-the-art technologies and medicinal chemistry developments
• PhD or MSc in organic chemistry or medicinal chemistry • Strong track record of delivery and breadth/depth of experience in an industrial drug discovery environment • 3–5 years of drug discovery experience • Good knowledge of synthetic and medicinal chemistry • Experience managing remote teams of medicinal and synthetic chemists at Contract Research Organisations • Solid understanding of biological signalling pathways, structure-based drug design, and ADME optimisation in drug discovery • Experience in preclinical drug discovery processes including hit identification, hit-to-lead, and lead optimisation through delivery of development candidates • Right to work in the UK • Nice to have: proficiency analysing and interpreting data from biophysical assays • Nice to have: familiarity with StarDrop, Spotfire, Vortex, or DataWarrior • Nice to have: experience across preclinical drug discovery from target selection and hit identification through delivery of development candidates across multiple programmes • Nice to have: experience assessing the patent landscape around a target • Nice to have: eagerness to develop leadership skills • Nice to have: understanding of cheminformatics and/or modelling software such as PyMol, KNIME, or Torx, and ability to use ML tools to predict assay endpoints • Nice to have: strong publication record in peer-reviewed journals and conference presentation experience
Postuler Maintenant🕒 il y a 22 jours
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