Director, Preclinical Program Leadership

🕒 May 22

🌽 Illinois – Remote

🌽 Illinois – Remote

💵 $175k - $250k / year

⏰ Full Time

🟠 Senior

👔 Director

👻 Ghost score 43%

What it means: how likely this posting is sitting open without active hiring.How to read it: 60% or higher means we think this is a ghost. Lower scores are less of a worry.How we score it: age, reposts, open roles vs team size, how fast jobs close, and whether pay is listed.Fine print: an estimate from public data, not a judgment of the company. Real jobs can score high, so treat it as a hint, not a fact.

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Evozyne

WebsiteLinkedInAll Job Openings

51 - 200 employees

Founded 2020

🏥 Healthcare

🧬 Biotechnology

💊 Pharmaceuticals

💰 $81M Series B - Evozyne on 2023-09

Healthcare • Biotechnology • Pharmaceuticals

Evozyne is an AI-native biotechnology company that designs de novo therapeutic proteins to treat immune‑mediated diseases. Its EvoGen generative AI engine designs protein sequences optimized for potency, stability, specificity, and low immunogenicity, and its EvoLab high-throughput experimental facility builds and tests thousands of candidates each design cycle to generate proprietary data. Evozyne advances engineered proteins—including IgG proteases, next‑generation cytokines, and respiratory disease candidates—toward clinical evaluation to address patients who do not respond to existing biologics or small molecules.

📋 Description

• Own program execution and operations from candidate nomination through IND clearance and Phase 1 enablement across multiple assets in parallel • Drive the critical path, including timelines, budgets, dependencies, and decision points • Build and maintain integrated development plans spanning multiple functional areas • Translate program progress into clear, actionable updates and recommendations for leadership • Own external partnerships with CROs and CDMOs, including vendor selection, scope definition, and ongoing performance management • Negotiate scope, cost, timelines, and deliverables, and hold partners accountable to outcomes • Coordinate across multiple vendors simultaneously, managing handoffs, data flow, and interdependencies • Partner with internal technical experts to design studies and translate program needs into effective external workstreams • Oversee development of study protocols, incorporating cross-functional input and aligning stakeholders • Build internal playbooks, processes, and operating structures needed to scale program execution across the pipeline • Report to the Chief Operating Officer • Advance therapeutic assets from candidate nomination through IND submission across multiple programs

🎯 Requirements

• Direct operational ownership of multiple IND programs in biologics, including at least one in functional protein therapeutics • Advanced degree in biochemical, pharmacology, toxicology, biology, life sciences, or a related field • 8+ years of relevant industry experience with a Ph.D. or 12+ years with a Master’s degree • Demonstrated success leading programs through CROs and CDMOs, including global vendors • Deep understanding of the drug development process from discovery through IND filing • Strong familiarity with GxP, ICH guidelines, and FDA preclinical requirements • Proven ability to align and influence stakeholders across functions and organizations • Strong strategic and operational judgment • Clear, concise communication and ability to simplify complex programs • Highly organized and detail-oriented, with ability to anticipate challenges • Hands-on leadership and comfort owning outcomes directly • Ability to influence without formal authority • Comfort operating in a fast-moving, evolving environment

🏖️ Benefits

• Opportunity to drive multiple programs from candidate nomination through IND and into the clinic in a highly integrated, fast-moving environment • Ability to work at the intersection of AI, biology, and experimental science • Significant ownership and influence on how preclinical programs are executed, prioritized, and scaled • Exposure to strategic decisions and hands-on execution in a lean team