Associate Principal Scientist – External Capabilities

🔥 18 hours ago

🌐 United Kingdom, China, +1 more countries – Remote

🇬🇧 United Kingdom – Remote 🇨🇳 China – Remote 🇮🇳 India – Remote

⏰ Full Time

🟢 Junior

🟡 Mid-level

🧬 Research Scientist

🇬🇧 UK Skilled Worker Visa Sponsor

This company has sponsored UK Skilled Worker visas in the past.

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MSD

WebsiteLinkedInAll Job Openings

10,000+ employees

Founded 1891

🏥 Healthcare

📦 Logistics

🧬 Biotechnology

Healthcare • Logistics • Biotechnology

MSD is a leading biopharmaceutical company known as Merck & Co. , Inc. in the United States, Canada, and Puerto Rico, and as MSD globally. The company focuses on scientific innovation to deliver medicines and vaccines for various health challenges, including oncology, vaccines, infectious diseases, and cardio-metabolic diseases. MSD operates multiple divisions, including Human Health, Animal Health, and Research & Development. With approximately 75,000 employees worldwide and a significant investment in research and development, MSD is committed to improving global health through its scientific advancements. Additionally, the company places a strong emphasis on diversity, inclusion, and corporate responsibility. MSD’s operations extend worldwide, offering opportunities in numerous regions and promoting diversity and innovation in all aspects of its business.

📋 Description

• Provide scientific leadership and day-to-day technical oversight for process chemistry activities at external partners • Guide synthetic route design, route scouting, process optimization, reaction understanding, impurity-control strategy, process robustness, and preparation of intermediates and APIs • Serve as the scientific interface between external partners and internal project teams • Evaluate experimental plans, data packages, development reports, and technical proposals • Identify scientific, operational, quality, and delivery risks and establish mitigation plans • Apply rigorous problem-solving to synthetic chemistry and process-development challenges • Collaborate with Process Chemistry, Discovery Process Chemistry, Enabling Technologies, Chemical Engineering R&D, Analytical R&D, Quality, and other functions • Contribute data-based recommendations to technical and strategic project decisions • Establish relationships with external partner scientists and management • Support knowledge transfer between external partners and internal teams • Promote scientific rigor, documentation, quality, data integrity, safety, and compliance • Contribute to external capability strategies, working practices, scientific standards, and continuous-improvement initiatives • Mentor colleagues and external-partner scientists as appropriate • Communicate project progress, technical risks, decisions, and recommended actions to stakeholders

🎯 Requirements

• Ph.D. in synthetic organic chemistry or a closely related field • Relevant pharmaceutical or biotechnology industry experience in synthetic chemistry, process chemistry, or closely related drug-development activities • Demonstrated ability to independently lead complex scientific activities and guide multidisciplinary or external project teams • Strong knowledge of synthetic organic chemistry, route design, process development, reaction optimization, impurity control, and scale-up considerations • Demonstrated record of delivering high-quality scientific results through innovation, sound judgment, and proactive problem-solving • Ability to analyze complex experimental data, identify technical risks, and recommend practical development strategies • Experience collaborating across scientific and operational functions • Strong interpersonal, written, and verbal communication skills • Effective negotiation, influencing, collaboration, and relationship-management skills • Ability to work across organizational boundaries, cultures, geographies, and time zones • Commitment to scientific excellence, data integrity, quality, safety, compliance, and ethical decision-making • Evidence of scientific contribution through publications, presentations, patents, internal technical reports, process-development accomplishments, or other relevant scientific impact • Ability and willingness to travel approximately 25% of the time • Preferred: experience overseeing work at contract development and manufacturing organizations or external R&D partners • Preferred: synthetic route development and process scale-up from laboratory studies through multikilogram or manufacturing-scale execution • Preferred: API delivery, technology transfer, external manufacturing, analytical control strategies, process safety, quality systems, regulatory expectations, multiple competing projects, mentoring, and external relationship management

🏖️ Benefits

• Remote work arrangement • Opportunity to work with diverse, talented, and committed colleagues in an inclusive environment • Travel approximately 25% of the time based on business needs