
Agriculture • Biotechnology
Pairwise is a biotechnology company applying CRISPR gene‑editing to develop improved plant varieties for agriculture. Using its proprietary Fulcrum™ platform—combining CRISPR tools, enzymes, trait libraries and AI-driven biology—Pairwise develops climate‑resilient, disease‑tolerant, higher‑yield and consumer‑oriented traits (e. g. , seedless blackberries, thornless and compact plants) and partners with major agriculture and consumer food companies to commercialize those traits. Founded in 2017 and based in Durham, NC, the company focuses on translating lab discoveries into licensed products and collaborations that benefit growers, consumers, and the planet.
51 - 200 employees
Founded 2017
🌾 Agriculture
🧬 Biotechnology
August 9

Agriculture • Biotechnology
Pairwise is a biotechnology company applying CRISPR gene‑editing to develop improved plant varieties for agriculture. Using its proprietary Fulcrum™ platform—combining CRISPR tools, enzymes, trait libraries and AI-driven biology—Pairwise develops climate‑resilient, disease‑tolerant, higher‑yield and consumer‑oriented traits (e. g. , seedless blackberries, thornless and compact plants) and partners with major agriculture and consumer food companies to commercialize those traits. Founded in 2017 and based in Durham, NC, the company focuses on translating lab discoveries into licensed products and collaborations that benefit growers, consumers, and the planet.
51 - 200 employees
Founded 2017
🌾 Agriculture
🧬 Biotechnology
• At Pairwise, we are a team of engineers, operators, and builders focused on enabling the next generation of technical talent to do their best work. We partner with leading technology companies to deliver high-performance engineering solutions across embedded systems, networking, semiconductors, and software. Our teams have contributed to some of the most advanced products in consumer, infrastructure, and communications technologies. • This full-time role offers the chance to work on-site with a global leader in the technology industry, contributing to impactful, technically challenging projects in a high-caliber and fast-moving environment. • Pairwise is reinventing technical staffing from the ground up, building an AI-powered platform to handle the entire employment lifecycle - from recruiting to offboarding. • We’re a small, experienced, and relentlessly driven team that ships fast and holds a high bar for quality. We're looking for a backend engineer who thrives in high-ownership environments, takes pride in clean architecture and well-designed systems, and wants to be part of an early team building critical infrastructure from scratch. • This is a rare opportunity to join early, influence both product and technical direction, and build the foundation of a company solving real problems at scale. • Design, build, and maintain scalable backend systems and APIs (Python/Django) • Translate product requirements into backend architecture and clean, maintainable code • Optimize performance across the stack - databases, queries, APIs • Support cloud infrastructure (Azure), ML model deployment, and devops workflows as needed • Help uphold high engineering standards through reviews, documentation, and technical planning
• 3+ years of backend experience with strong Python skills and production Django or similar framework experience • Deep understanding of databases, schema design, SQL, and performance tuning (PostgreSQL preferred) • Experience with cloud environments (Azure preferred; AWS/GCP also relevant) and infrastructure tooling • Bonus: Familiarity with ML infrastructure (e.g. model serving, GPU clusters), parallel processing, or frontend work (React/JS) • Degree in Computer Science or equivalent experience; MS/PhD a plus
• Pairwise offers competitive compensation and access to a range of benefits for employees, including premium PPO and HMO medical insurance coverage, dental, vision, FSA, life insurance, short/long-term disability insurance, a company-matched 401k plan, and a generous PTO policy.
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