Senior Full-Stack Engineer

🕒 September 3

🇺🇸 United States – Remote

💵 $90k - $110k / year

⏰ Full Time

🟠 Senior

🧑‍💻 Full-stack Engineer

👻 Ghost score 0%

What it means: how likely this posting is sitting open without active hiring.How to read it: 60% or higher means we think this is a ghost. Lower scores are less of a worry.How we score it: age, reposts, open roles vs team size, how fast jobs close, and whether pay is listed.Fine print: an estimate from public data, not a judgment of the company. Real jobs can score high, so treat it as a hint, not a fact.

Apply Now

Find Similar Remote Jobs

Set Up Email Alert For New Jobs

📊 Check your resume score for this job

Improve your chances of getting an interview by checking your resume score before you apply.

Upload Resume

Simulations Plus, Inc.

WebsiteLinkedInAll Job Openings

201 - 500 employees

Founded 1996

💊 Pharmaceuticals

🧬 Biotechnology

☁️ SaaS

💰 Grant - Simulations Plus on 2024-11

Pharmaceuticals • Biotechnology • SaaS

Simulations Plus, Inc. is a science-driven software and consulting company that provides mechanistic modeling, AI-enabled workflows, and expert services to support model‑informed drug development (MIDD) across discovery, development, clinical operations, and commercialization. Its product suite includes GastroPlus (PBPK/PBBM), MonolixSuite (pharmacometrics), ADMET Predictor (ML for ADMET), DILIsym (quantitative systems toxicology), Thales (QSP), and Pro‑ficiency (learning/simulation), and the company offers consulting, training, regulatory strategy support, and bundled solution packages. Simulations Plus emphasizes mechanistic and AI-enabled tools for ADMET prediction, PBPK, pharmacometrics, QSP/QST and serves pharmaceutical and biotech clients (noting ~30+ years in business, ~280+ clients and use by 19 of the top 20 pharma companies).

📋 Description

• Own features end-to-end across Node.js and Express backends and React/Tailwind frontends • Build APIs, user interfaces, and data flows behind customer-facing functionality • Contribute to the platform's data, authentication, and service patterns • Integrate LLM-powered functionality into product surfaces alongside the AI lead • Connect frontends to LLM and MCP endpoints • Handle streaming, errors, and degraded states gracefully • Contribute to evaluations, fixtures, and tooling supporting AI development • Bring full-stack range across backend, frontend, and AI work • Contribute to code reviews, documentation, and shared engineering practices • Apply AI coding tools effectively in the daily engineering workflow • Perform other duties as assigned

🎯 Requirements

• 3+ years of professional software engineering experience, with shipped full-stack work in production • Proficiency in JavaScript or TypeScript across Node.js backend and React frontend • Practical experience with document or NoSQL databases such as MongoDB • Comfort building and consuming REST APIs and JSON contracts • Genuine interest in agents, MCP, and applied AI, and the drive to build real expertise in those areas • Fluency using AI coding tools (Claude, Cursor, Copilot) in daily workflow • Familiarity with Anthropic, OpenAI, or other LLM provider SDKs • Exposure to MCP, agent frameworks, or LLM-integrated product features • Experience with cloud infrastructure (AWS preferred) and CI/CD pipelines • Experience in regulated-software environments (SOC 2, HIPAA, GxP, 21 CFR Part 11) or life-sciences SaaS • Familiarity with Passport, OAuth, OIDC, or comparable auth patterns • Bachelor's degree in computer science, engineering, or related field preferred • Relevant technical certifications welcomed

🏖️ Benefits

• Fully remote work • Flexible schedules • Generous vacation policy • Affordable health coverage • Annual bonus