Principal Scientist, PK/PD

🕒 April 14

🇺🇸 United States – Remote

💵 $114k - $185k / year

⏰ Full Time

🔴 Lead

🧬 Research Scientist

🦅 H1B Visa Sponsor

This company has sponsored H1B visas in the past.

👻 Ghost score 45%

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Zoetis

WebsiteLinkedInAll Job Openings

10,000+ employees

Founded 1952

🏥 Healthcare

🍽️ Food & Beverage

🏭 Manufacturing

Healthcare • Food & Beverage • Manufacturing

Zoetis is the world's leading animal health company, committed to nurturing the world and humankind by advancing care for animals. With over 70 years of innovation, Zoetis develops a broad portfolio and pipeline of medicines, vaccines, diagnostics, and technologies that span a continuum of care to predict, prevent, detect, and treat animal illnesses. Operating in more than 100 countries, the company supports livestock farmers, veterinarians, and pet owners around the globe. Zoetis is driven by science and their shared passion for the human-animal bond, aiming to create a more sustainable and healthier world for all.

📋 Description

• Independently design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports • Provide PK and PK/PD modeling and simulation to select lead candidates and optimize dose regimens • Collaborate with the bioanalytical team to assess analytical assay suitability and forecast analytical requirements • Lead scientific strategy development across therapeutic areas, focusing on mechanistic platforms and biomarkers • Support translation, target engagement measurement, and dose regimen predictions • Collaborate with multidisciplinary teams to design and conduct studies aligned with project strategy • Present research results to scientific teams, management, and regulatory agencies • Write sections of regulatory submissions, respond to regulatory agency inquiries, and maintain knowledge of regulatory guidance documents

🎯 Requirements

• Ph.D in pharmacology, biochemistry, or related field • 4 or more years of relevant pharmaceutical development experience • Proven ability to design, analyze and interpret in vivo PK and PK/PD studies • Experience with biotherapeutics (protein therapeutics) is highly desirable • Skilled in PK and PK/PD analysis software such as WinNonlin, Monolix or Watson • Excellent verbal and written communication skills • Ability to prioritize work and work efficiently with minimal supervision • Working knowledge of bioanalytical methodology • Knowledge of ADA assays and assessment of immunogenicity of biotherapeutics is highly desirable • Experience in PK/PD modeling and simulation such as PBPK, QSP or population PK modeling using NONMEM, R, or related software is highly desirable • Experience interacting with regulatory agencies is highly desirable • Experience conducting GLP studies is desirable • All applicants must possess or obtain authorization to work in the US for Zoetis • DVM DACVCP or DVM Dipl. ECVPT is highly desirable

🏖️ Benefits

• Short-term incentive compensation • Long-term incentives • Healthcare and insurance benefits beginning on day one • 401K plan with a match • Profit-sharing contribution from Zoetis • 4 weeks of vacation

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