AD/Director, Toxicology

Vaga não está no LinkedIn

🕒 Fevereiro 25

🏄 California – Remoto

🏄 California – Remote

💵 $181.900 - $239.700 / ano

⏰ Tempo Integral

🔴 Especialista

👔 Diretor

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BBOT

SiteLinkedInTodas as Vagas

51 - 200 funcionários

🧬 Biotecnologia

💊 Farmacêutico

Biotechnology • Pharmaceuticals

BBOT é uma empresa de biotecnologia que desenvolve terapias direcionadas para cânceres impulsionados pelo sinal RAS e PI3Kα. A empresa foca em design racional de medicamentos para inibir o estado ativo de RAS e bloquear seletivamente a ativação de PI3K impulsionada por RAS, visando múltiplos mutantes KRAS e novas abordagens para maximizar a inibição do alvo. BBOT traduz décadas de pesquisa em biologia do RAS em candidatos terapêuticos destinados a melhorar os resultados para pacientes com tumores impulsionados por RAS e PI3Kα.

Descrição

• Lead and own all in vitro and in vivo non-clinical toxicology activities (non-GLP & GLP) for multiple programs • Design and communicate customized toxicology strategies for each program • Attend program meetings, collaborate with cross-functional team leads, and guide project team leaders regarding toxicology and safety plans and timelines • Plan, design, and oversee the execution of all outsourced CRO collaborations for toxicology and safety studies • Manage, edit, and finalize collaborators’ (CRO) study reports • Analyze, interpret, present, and communicate all preclinical toxicology and safety study findings • Make key recommendations to project teams for mitigation strategies and next steps • Author high-quality regulatory documents to support filings such as IND, CTA, NDA, and IB

🎯 Requisitos

• Ph.D. in Toxicology, Pharmacology, Biology, or a related field; DABT preferred but not required • 5+ years of professional experience in toxicology research or drug development in an industry setting; small molecule experience required • Experience working with CROs in the US, Canada, EU, and Asia • Professional level proficiency speaking English is required • Professional level proficiency speaking Chinese is preferred

🏖️ Benefícios

• Competitive salary, benefits, and meaningful equity participation in a public company • Annual bonus • Stock-based long-term incentives • Medical, dental, and vision benefits • Retirement • Wellness stipend • Flexible time off