Manager of Bioinformatics – Women's Health, Organ Health

🕒 Agosto 10

🇺🇸 Estados Unidos – Remoto (EUA)

💵 $140.000 - $175.000 / ano

⏰ Tempo Integral

🟡 Pleno

🟠 Sênior

👔 Gerente

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Natera

SiteLinkedInTodas as Vagas

1001 - 5000 funcionários

Fundada em 2004

🏥 Saúde

🧬 Biotecnologia

⚕️ Seguro de Saúde

Healthcare • Biotechnology • Healthcare Insurance

A Natera é líder global em tecnologia de testes de DNA livre de células (cfDNA), especializada em testes e diagnósticos genéticos não invasivos. As soluções inovadoras da empresa concentram-se em áreas como triagem pré-natal, detecção de câncer e monitoramento de transplantes de órgãos. Ao utilizar bioinformática avançada e análise de DNA, a Natera oferece a profissionais de saúde e pacientes informações essenciais para decisões médicas mais embasadas.

Descrição

• Lead production support for bioinformatics and data science algorithms behind Women's Health and Organ Health products • Lead a team of Data and Bioinformatics Scientists accountable for algorithm behavior on real samples • Own the interface between the Data and Bioinformatics Scientists and the production organization • Resolve inconclusive reports by assessing technical constraints and data quality issues • Determine upstream process changes to reduce inconclusive cases • Maintain a catalogue of known patterns for matching new cases to settled cases • Use AI to assemble and help interpret evidence during triage • Coordinate with Production Engineering, Product, the laboratory, and R&D to align changes in direction and scope • Define service commitments for turnaround and coverage • Build the processes and staffing needed to meet service commitments • Own production support and ensure answers are correct and timely • Lead cross-system investigations and identify ownership of fixes • Convert one-off investigations into durable rules and design changes • Own process validation for pipeline and algorithm changes • Define evidence requirements before changes enter sample-running workflows • Lead, hire, and develop Data and Bioinformatics Scientists • Partner with Production Engineering, Product, Bio Development, laboratory operations, and Data Science R&D • Establish standards for agent-assisted investigation and determine when conclusions require manual reproduction • Reduce recurring escalations and test turnaround time • Establish and maintain change validation and support processes

🎯 Requisitos

• M.S. or Ph.D. in Bioinformatics, Computational Biology, Data Science, or a related technical discipline, or equivalent depth built through work • 5+ years working with genomic or sequencing data • 2+ years leading people • Demonstrated ownership of a support, escalation, or on-call function with commitments attached • Experience leading investigations across more than one system boundary through resolution • Ability to reach agreement across organizational lines without authority • Sequencing and bioinformatics fluency sufficient to distinguish pipeline failures from expected behavior • Ability to reconstruct events from logs, intermediate files, and pipeline outputs • Python and SQL for investigation, record retrieval, run comparison, and tool building • Experience with change control, validation, and documentation practices • Experience defining support processes, setting commitments, securing agreement, and staffing appropriately • Demonstrated people leadership, including developing, hiring, or repositioning team members • Understanding of laboratory operations and upstream data issues • Senior-level communication, negotiation, and persuasion skills • Machine learning or statistical analysis applied to genomic data is useful but not a gate • Experience with cell-free DNA, prenatal, or carrier screening applications is advantageous • Experience in an accredited or high-complexity laboratory or regulated diagnostic setting is advantageous • Familiarity with WDL, Nextflow, Snakemake, or Cromwell is advantageous • Experience building observability or alerting is advantageous

🏖️ Benefícios

• Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents • Free testing for Natera employees and their immediate families • Fertility care benefits • Pregnancy and baby bonding leave • 401k benefits • Commuter benefits • Generous employee referral program