Director, Global Value and Health Economics

🕒 il y a 1 jour

🏄 California, Pennsylvania – Distant

infoinfo

💵 $212 000 - $318 000 / an

⏰ Temps Plein

🔴 Expert

👔 Directeur

🗣️🇺🇸🇬🇧 Anglais requis

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Jazz Pharmaceuticals

1001 - 5000 employés

Fondée en 2003

🏥 Santé

🏭 Fabrication

🧬 Biotechnologie

Healthcare • Manufacturing • Biotechnology

Jazz Pharmaceuticals est une entreprise biopharmaceutique dédiée au développement de médicaments innovants répondant à des besoins médicaux sérieux non satisfaits. Avec un fort engagement envers la recherche et le développement, Jazz se concentre sur la création de thérapies transformatrices, mettant en avant l'importance de la collaboration, de la diversité et de l'engagement des employés dans ses opérations. L'entreprise est fière de transformer la vie des patients grâce à ses offres de produits significatives et une culture qui favorise l'enthousiasme et la flexibilité.

Description

• Lead global and US payer evidence strategy across marketed assets in Jazz’s neurology portfolio • Maximize brand potential, defend value, secure expanded access, and drive evidence generation across the post-launch lifecycle • Translate commercial, access, and policy priorities into evidence generation plans and deliverables • Lead HEOR evidence strategies supporting supplemental regulatory filings, new indications, line extensions, expanded subpopulations, and novel formulations/devices • Optimize Phase 3b/4 trials, pragmatic studies, and expanded access programs with payer-relevant endpoints, PROs, and HRQoL measures • Partner with Market Access on indication sequencing and access strategy • Lead rare disease registries, natural history extensions, and post-authorization safety/efficacy studies • Design comparative effectiveness, adherence, burden-of-illness, and real-world data studies to defend product value • Co-create HTA re-assessment strategies and deliver updated NMAs, ITCs, economic models, and evidence packages • Direct updates of Global Value Dossiers, systematic literature reviews, and meta-analyses • Serve as designated US HEOR expert for assigned inline products • Lead AMCP dossiers, unbranded value summaries, and state Medicaid submission dossiers • Develop and train teams on interactive economic models and reactive scientific presentations • Ensure US HEOR deliverables comply with FDAMA Section 114, the 21st Century Cures Act, and FDA HCEI guidance • Evaluate outcomes-based risk-sharing agreements and establish real-world endpoint tracking frameworks • Monitor US health policy and prepare evidence plans and materials for ICER and other value assessment bodies • Build and adapt cost-effectiveness, cost-utility, budget impact, cost-offset, Markov, partitioned survival, microsimulation, and dynamic population models • Govern Integrated Evidence Generation Plans for inline assets • Partner with Market Access, Medical Affairs, Commercial Brand, Regulatory Affairs, Biostatistics, and RWE teams • Lead publications and conference presentations at ISPOR, AMCP, and disease-specific congresses • Manage vendors, consultancies, academic partners, CROs, budgets, quality, timelines, and compliance • Provide mentorship and technical guidance to associate directors, managers, and fellows

🎯 Exigences

• Master’s degree (MSc, MS, MPH) or PhD in Health Economics, Outcomes Research, Pharmacoeconomics, or a closely related quantitative field • Minimum of 7–10 years of experience in HEOR, Global Value, or Health Economics within the biopharmaceutical industry or a top-tier HEOR consulting firm • Extensive experience designing and executing post-marketing HEOR strategies, real-world comparative effectiveness studies, and evidence roadmaps supporting label expansions, line extensions, and value defense • Comprehensive working knowledge of the US managed care landscape and global HTA environments • Proven technical expertise building, adapting, and validating economic models, including Markov, partitioned survival, microsimulation, and dynamic budget impact models • Proven track record collaborating with US Market Access, Pricing/Contracting, and Payer Field Teams • Demonstrated understanding of rare disease and orphan product post-launch evidence challenges • Working knowledge of major US and global healthcare databases and advanced epidemiological methods • Ability to balance evidence strategy with hands-on execution of complex technical deliverables • Exceptional verbal, written, and presentation skills • Demonstrated ability to influence cross-functional matrix teams and defend methodologies before payers, HTA authorities, and scientific reviewers • Experience with neurology assets preferred • Demonstrated track record leading HEOR strategy and executing evidence deliverables for marketed pharmaceutical products • Launch lead for at least 2 assets as US HEOR lead, or country-level HTA lead • Experience conducting post-marketing RWE, patient registry studies, and economic evaluations in rare diseases, specialized medicine, or complex chronic conditions • Substantial experience collaborating with regional HEOR teams to deliver global HTA re-assessment packages • Strong peer-reviewed publication record in health economics and outcomes research

🏖️ Avantages

• Discretionary annual cash bonus or incentive compensation • Discretionary equity grants through the Long Term Equity Incentive Plan • Medical insurance • Dental insurance • Vision insurance • 401k retirement savings plan • Flexible paid vacation

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