Director, Global Value, Health Economics and Outcomes Research

🕒 il y a 1 jour

🏄 California, Pennsylvania – Distant

infoinfo

💵 $212 000 - $318 000 / an

⏰ Temps Plein

🔴 Expert

👔 Directeur

🗣️🇺🇸🇬🇧 Anglais requis

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Jazz Pharmaceuticals

1001 - 5000 employés

Fondée en 2003

🏥 Santé

🏭 Fabrication

🧬 Biotechnologie

Healthcare • Manufacturing • Biotechnology

Jazz Pharmaceuticals est une entreprise biopharmaceutique dédiée au développement de médicaments innovants répondant à des besoins médicaux sérieux non satisfaits. Avec un fort engagement envers la recherche et le développement, Jazz se concentre sur la création de thérapies transformatrices, mettant en avant l'importance de la collaboration, de la diversité et de l'engagement des employés dans ses opérations. L'entreprise est fière de transformer la vie des patients grâce à ses offres de produits significatives et une culture qui favorise l'enthousiasme et la flexibilité.

Description

• Define and drive global and US payer evidence strategy for pipeline assets from Phase 2/3 through regulatory approval and launch • Lead global payer evidence generation while serving as the US HEOR lead • Develop US pre-launch HEOR deliverables, payer field enablement tools, and US market access evidence strategies • Translate target product profiles and access ambitions into evidence generation programs • Partner with Clinical Development, Biostatistics, and Clinical Operations to integrate payer, formulary, and HTA requirements into Phase 2/3 trial designs • Optimize trial protocols, comparators, inclusion/exclusion criteria, treatment lines, and endpoints • Integrate PROs, HRQoL, symptom burden scales, and HCRU instruments into pivotal trials • Design evidence strategies for rare disease assets using natural history data, biomarkers, and external or historical comparator cohorts • Lead health economic modeling strategies, including conceptual models, threshold analyses, CEAs, and BIMs • Direct design, development, and validation of adaptable global core economic models • Lead US AMCP PIE dossiers, burden-of-illness dossiers, and US budget impact models • Design payer-facing economic models, evidence slide decks, and population health tools • Support ICER evaluations, IRA planning, and CMS price negotiation readiness • Lead HEOR workstreams within Launch Readiness Teams and oversee global launch evidence assets • Co-develop EU/INT HTA strategies and analytical packages for JCA, NICE, G-BA, CADTH, and other bodies • Design and execute pre-launch real-world studies, chart reviews, registries, and burden-of-illness evaluations • Govern the Integrated Evidence Generation Plan and coordinate cross-functional evidence priorities • Develop scientific publication plans, manuscripts, and congress presentations • Mentor junior HEOR scientists, post-doctoral fellows, and matrix colleagues

🎯 Exigences

• Master’s degree (MSc, MS, MPH, PhD) in Health Economics, Outcomes Research, Pharmacoeconomics, or a closely related quantitative field • Minimum of 7–10 years of experience in HEOR, Global Value, or Health Economics within the biopharmaceutical industry or a top-tier HEOR consulting firm • Experience with neurology assets preferred • Direct experience leading HEOR strategy and deliverables for pipeline assets, including early Phase 2/3 clinical trial protocol integration, endpoint development, and global launch readiness • Experience managing regional trade offs on evidence needs as part of Phase 2/3 protocol development • Launch lead for at least 2 assets as US HEOR lead, or country level HTA lead • Proven track record serving as the US HEOR lead or driving US pre-launch HEOR deliverables • Preferred direct experience in rare disease, orphan drug, or highly specialized pipeline programs • Demonstrated hands-on experience designing, overseeing, or adapting health economic models • Demonstrated track record collaborating with regional HEOR teams • Deep expertise in health economic modeling, including Markov state-transition, partitioned survival, microsimulation, and decision-tree models • Familiarity with US managed care and market access, Medicare Advantage, Medicare Part D/B, Medicaid, PBMs, and global HTA frameworks • Experience with GVDs, AMCP PIE dossiers, global ITCs/NMAs, US budget impact models, natural history studies, registries, external control arms, and specialized HTA pathways • Exceptional written and verbal communication skills, with an established record of HEOR and clinical publications or HTA success

🏖️ Avantages

• Discretionary annual cash bonus or incentive compensation • Discretionary equity grants • Medical insurance • Dental insurance • Vision insurance • 401k retirement savings plan • Flexible paid vacation

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