Director, CAR T Channel Strategy – Operations

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Kyverna Therapeutics

Site WebLinkedInTous les Emplois

51 - 200 employés

Fondée en 2019

🧬 Biotechnologie

💊 Pharmaceutique

🔬 Science

💰 €85 000 000 Series B en 2022-01

Biotechnology • Pharmaceuticals • Science

Kyverna Therapeutics est une entreprise biopharmaceutique en phase clinique, axée sur le patient, qui développe des thérapies cellulaires pour les patients souffrant de maladies auto-immunes. L'entreprise est pionnière dans les thérapies CAR T-cell, tirant parti du pouvoir transformationnel des cellules T pour potentiellement offrir une rémission durable sans traitement pour les maladies auto-immunes. Le principal candidat de thérapie CAR T-cell de Kyverna, KYV-101, progresse à travers des essais cliniques ciblant diverses maladies auto-immunes, y compris la sclérose en plaques, la myasthénie grave, la sclérodermie systémique et la néphrite lupique. Leur pipeline comprend des thérapies innovantes utilisant des récepteurs antigéniques chimériques (CAR) T-cell, tant dans les formats autologues qu'allogéniques, destinées aux maladies auto-immunes médiées par les cellules B.

Description

• Develop and execute channel strategies that balance customer experience, operational efficiency, compliance requirements, and gross-to-net (GTN) optimization. • Serve as business owner for third-party logistics (3PL) partnerships and distribution operations supporting CAR T commercialization. • Lead specialty pharmacy and distribution strategy development to support current and future portfolio needs. • Partner with Market Access, Finance, Commercial, and Legal teams to evaluate channel design alternatives and their impact on GTN performance. • Assess channel economics and recommend strategies that optimize reimbursement, contracting, distribution costs, and commercial profitability while maintaining customer satisfaction. • Oversee state licensing strategy, renewals, compliance requirements, and regulatory readiness. • Support government pricing activities through cross-functional coordination, process governance, and operational oversight. • Lead distribution governance, service-level management, and operational performance reviews across external partners. • Support launch planning, market expansion, and new product introductions through scalable channel infrastructure. • Develop reporting, analytics, and performance metrics that provide visibility into channel effectiveness and operational health. • Identify and mitigate operational, regulatory, and commercial risks across the distribution network.

🎯 Exigences

• Bachelor’s degree required; advanced degree preferred. • 10+ years of experience in biotechnology, pharmaceutical, specialty distribution, market access, commercial operations, or related functions. • Experience developing and executing channel strategies for specialty pharmaceuticals, cell therapies, gene therapies, or other complex therapies. • Strong understanding of gross-to-net (GTN) principles, channel economics, distribution agreements, and commercial contracting. • Demonstrated ability to design channel solutions that optimize GTN performance while meeting customer, provider, and patient requirements.

🏖️ Avantages

• bonus • benefits • participation in Company’s stock plan