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Associate Director of Bioinformatics – Women's Health, Organ Health

🕒 vor 2 Monaten

🇺🇸 Vereinigte Staaten – Remote

💵 $166.600 - $202.000 / Jahr

⏰ Vollzeit

🟠 Senior

👔 Direktor

🗣️🇺🇸🇬🇧 Englisch erforderlich

Woher diese Stelle stammt

Veröffentlicht auf der Karriereseite von Natera, nicht über eine Jobbörse

Von Remote Rocketship zum ersten Mal gesehen vor 2 Monaten

Noch offen auf der Website von Natera. Geprüft vor 4 Stunden.

Logo of Natera

Natera

1001 - 5000 Mitarbeiter

Gegründet 2004

🏥 Gesundheitswesen

🧬 Biotechnologie

⚕️ Krankenversicherung

Healthcare • Biotechnology • Healthcare Insurance

Natera ist ein weltweit führendes Unternehmen in der Technologie der zellfreien DNA-Tests, das sich auf nicht-invasive genetische Tests und Diagnostik spezialisiert hat. Die innovativen Lösungen des Unternehmens konzentrieren sich auf Bereiche wie pränatales Screening, Krebstestung und Überwachung von Organtransplantationen. Durch den Einsatz fortschrittlicher Bioinformatik und DNA-Analysen bietet Natera medizinischen Fachkräften und Patienten entscheidende Informationen, um fundiertere medizinische Entscheidungen treffen zu können.

Beschreibung

• Lead and mentor a team of Bioinformatics Scientists and own their professional growth and responsibilities • Own research strategy for new product development from scoping through execution • Lead bioinformatics analysis for assay development and optimization • Troubleshoot experiments with laboratory scientists across methylation, fragmentomics, cfDNA features, short-read and long-read sequencing, hybrid-capture, and amplicon enrichment • Partner with laboratory teams on study design, technology assessment, optimization, and performance determination • Advise and prototype improvements to analysis pipelines, including variant detection, quality control, methylation calling, fragment-size and end-motif analysis, error suppression, and structural-variant calling • Move research prototypes into stable production workflows • Enforce software engineering practices including version control, testing, CI/CD, and containerization • Automate research data management, pipeline execution, and reporting • Establish standards for appropriate AI agent-assisted work and scientific sign-off • Collaborate with data science, molecular biology, pipeline engineering, biostatistics, quality assurance, and laboratory operations • Serve as a bioinformatics subject-matter expert and communicate findings and roadmaps across the company • Ensure research roadmaps are visible, methods reach production code, benchmark performance is demonstrated, and cross-functional teams can independently support decisions

🎯 Anforderungen

• Ph.D. in Bioinformatics, Computational Biology, Computer Science, Mathematics, Engineering, Biostatistics, or a related field; an M.S. with equivalent experience considered • 7+ years in bioinformatics, including 3+ years leading scientists and working across functions • Demonstrated ownership of a team that took scientific research into real clinical use • Demonstrated experience developing or scientifically guiding diagnostic sequencing assays • Deep expertise in next-generation sequencing analysis, including hybrid-capture or amplicon-based target enrichment, sequencing quality control, secondary analysis, and variant calling • Experience with cell-free DNA sequencing and other omics data, especially in a diagnostics setting • Working knowledge of diagnostic product development in a regulated, accredited setting • Strong Python, programming, and data analysis skills • Fluency in exploratory data analysis and visualization on complex datasets • Understanding of sequencing workflows from sample extraction through the instrument • Record of assessing a new platform, assay chemistry, or method against established benchmarks • Strong communication of technical detail to non-specialists • Ability to manage several objectives and timelines without close supervision • Long-read sequencing with PacBio HiFi or Oxford Nanopore in addition to short-read Illumina, R, shell scripting, Java, AWS, GCP, Snakemake, WDL, Nextflow, Cromwell, Docker, Kubernetes, conference presentations, or peer-reviewed publication are additional strengths

🏖️ Vorteile

• Comprehensive medical, dental, vision, life and disability plans for eligible employees and dependents • Free testing for employees and immediate families • Fertility care benefits • Pregnancy and baby bonding leave • 401(k) benefits • Commuter benefits • Employee referral program • Equal Opportunity Employer and inclusive workplace

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