Senior Manager, Portfolio Analytics – Strategy

🕒 August 10

🏄 California – Remote

🏄 California – Remote

💵 $141.5k - $191.4k / year

⏰ Full Time

🟠 Senior

👔 Manager

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Amgen

WebsiteLinkedInAll Job Openings

10,000+ employees

Founded 1980

🏥 Healthcare

🧬 Biotechnology

💊 Pharmaceuticals

💰 $28.5G Post-IPO Debt on 2022-12

Healthcare • Biotechnology • Pharmaceuticals

Amgen is a global leader in biotechnology, focusing on the development and commercialization of innovative medicines made from living cells. The company aims to treat serious illnesses, often targeting diseases with limited therapeutic options. Amgen emphasizes scientific innovation and is committed to ethical research, patient safety, and environmental sustainability. It actively engages in clinical trials and is known for its contributions to the fields of cancer treatment and obesity management among others.

📋 Description

• Lead portfolio analysis, performance tracking, and benchmarking across the R&D portfolio • Own and evolve Amgen’s Probability of Technical and Regulatory Success (PTRS) process • Facilitate enterprise PTRS assessments with Product Teams and cross-functional experts • Develop PTRS methodology, standards, benchmarks, guardrails, governance cadence, and documentation • Oversee PTRS and risk-assessment tools, data products, evidence workflows, dashboards, and decision-support capabilities • Partner with Product Teams to assess risk across product profiles, indications, populations, biomarker strategies, and clinical development options • Facilitate evidence-based discussions and clarify assumptions, risks, trade-offs, and decision criteria • Support portfolio reviews, prioritization, and investment decisions • Lead portfolio performance tracking and industry benchmark participation across development KPIs • Deliver decision-ready insights for Product Teams, Governance, and senior leadership • Maintain consistency across PTRS, valuation, planning, and governance assumptions • Use historical outcomes, internal performance trends, and external benchmarks to calibrate assessments and improve decision quality • Collaborate with Technology, Research, Development, Product Teams, and other cross-functional partners

🎯 Requirements

• Doctorate degree and 2 years of experience in R&D portfolio management, portfolio analytics, life sciences or management consulting, or leading decision analysis initiatives; OR • Master’s degree and 4 years of relevant experience; OR • Bachelor’s degree and 6 years of relevant experience; OR • Associate’s degree and 10 years of relevant experience; OR • High school diploma/GED and 12 years of relevant experience • Advanced degree in business, life sciences, medicine, statistics, decision sciences, or a related field preferred • 5+ years of experience in relevant R&D portfolio management, portfolio analytics, life sciences, management consulting, or decision analysis initiatives preferred • Working knowledge of decision analysis methodologies and probabilistic modeling techniques, such as decision trees, Monte Carlo simulation, and risk modeling • Experience facilitating PTRS, probability of success, or comparable development risk assessments with cross-functional subject matter experts • Deep understanding of the end-to-end drug development process and scientific, clinical, regulatory, CMC, operational, and competitive risk factors • Comfort using AI-enabled tools and analytical capabilities for evidence synthesis, risk assessment, insight development, and decision support • Strong analytical and strategic thinking skills • Executive presence and exceptional communication skills • Ability to thrive in a fast-paced, ambiguous, and highly matrixed environment

🏖️ Benefits

• Comprehensive employee benefits package • Retirement and Savings Plan with generous company contributions • Group medical, dental and vision coverage • Life and disability insurance • Flexible spending accounts • Discretionary annual bonus program • Stock-based long-term incentives • Award-winning time-off plans • Flexible work models where possible • Career development opportunities • Work/life balance support • Collaborative culture • Reasonable accommodation for disabilities