Principal Scientist, Medical Physicist

🕒 September 21

🇺🇸 United States – Remote

💵 $134.5k - $163k / year

⏰ Full Time

🔴 Lead

🧬 Research Scientist

🦅 H1B Visa Sponsor

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👻 Ghost score 13%

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Logo of Bristol Myers Squibb

Bristol Myers Squibb

10,000+ employees

Founded 1887

🏥 Healthcare

💼 Consulting

📦 Logistics

Healthcare • Consulting • Logistics

Bristol Myers Squibb is a global biopharmaceutical company that is dedicated to discovering, developing, and delivering innovative medicines that help patients prevail over serious diseases. Their areas of focus include cardiovascular health, cell therapy, immunology, and oncology. With a commitment to transforming patient outcomes through pioneering science, Bristol Myers Squibb partners with a worldwide network of researchers, healthcare providers, and other stakeholders. They aim to lead in innovation for patients while fostering diversity and inclusion within their workforce.

📋 Description

• Apply radiopharmaceutical-specific modeling expertise to research and development of new drugs and therapies • Lead radiopharmaceutical dose modelling and analyze in vitro, in vivo, clinical diagnostic, and therapeutic study data • Lead translational dosimetry analysis, including physiologically based pharmacokinetic and compartmentalization modelling • Provide technical support, including dosimetry calculations • Collaborate with internal stakeholders, external vendors, and experts • Support internal dosimetry analysis for radiopharmaceutical imaging and therapeutic agents across discovery and development • Design experiments with Discovery and analyze dosimetric data from PET and SPECT imaging to assess drug uptake and distribution • Identify and advise best practices and standardization processes for preclinical image data quality control • Analyze preclinical and clinical imaging data to advance animal-to-human dose projection • Explore new technologies, modelling approaches, and novel radioisotopes such as alpha-emitters • Contribute to medical physics knowledge in radiopharmaceuticals • Provide technical support, training, and problem-solving solutions to cross-functional teams • Apply AI to improve team execution and decision-making

🎯 Requirements

• Advanced degree in Medical Physics or Engineering with didactic training in RPT biodistribution, kinetics and dose modelling • Minimum of 6 years of experience in molecular imaging and RPT dose modelling research, or 3 years of extensive RPT-specific publications (10+) • Experience with radiopharmaceuticals as therapeutics in oncology strongly desired • Experience with alpha-emitters strongly desired • Subject Matter Expert in mathematical pharmacokinetic modeling and its application in radiopharmaceutical research and development • Technical skills with dosimetry software, coding, and simulation/modeling/statistical tools, including 3D-RD-S, MIM, MIRDcalc, OLINDA, Torch, GATE, SIMIND, SAAM II, SimBiology, Python, Matlab, R, SPSS, ITK-snap, 3D slicer, and Elastix • Current knowledge of global dosimetry guidelines a plus • Willingness to travel when needed (10-15%), including conference attendance that may involve evening and weekend work • Ability to communicate clearly and think creatively on multidisciplinary projects • Ability to coordinate and align cross-functional stakeholders to deliver on corporate timelines • Ability to organize, prioritize, and work effectively with minimal supervision in a constantly changing environment • Recognized leadership skills, professional ethics, integrity, and ability to maintain confidential information • Ability to meet physical demands, including occasionally lifting or moving up to 50 pounds

🏖️ Benefits

• Additional discretionary incentive cash and stock opportunities • Wellbeing support • Retirement and financial protection benefits • Medical, dental, vision, life and disability insurance offerings • Flexible Time Off (FTO) without a set accrual limit for U.S.-based exempt employees • 11 paid company holidays each year • 160 hours of paid vacation annually for new hires for non-exempt employees, RayzeBio employees, and employees located in Puerto Rico • 3 optional holidays for non-exempt employees, RayzeBio employees, and employees located in Puerto Rico • Paid sick leave, depending on eligibility • Up to two paid volunteer days per year, depending on eligibility • Summer hours flexibility • Leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs • Annual Global Shutdown between Christmas Day and New Year's Day for eligible employees • Reasonable workplace accommodations/adjustments and ongoing support for people with disabilities

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