Senior Biological Data Scientist

🕒 August 4

🇺🇸 United States – Remote

💵 $155k - $205k / year

⏰ Full Time

🟠 Senior

📊 Data Scientist

🦅 H1B Visa Sponsor

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BridgeBio

201 - 500 employees

Founded 2015

🏥 Healthcare

🧬 Biotechnology

💊 Pharmaceuticals

Healthcare • Biotechnology • Pharmaceuticals

BridgeBio is a biotechnology company focused on designing transformative medicines for patients with genetic diseases. It employs a novel approach to drug development by integrating finance with science to deliver solutions as efficiently as possible. The company is committed to developing not only life-changing drugs but also leaders in the field, encouraging hands-on engagement and the pursuit of innovation. BridgeBio actively seeks investment to help achieve its mission of providing solutions for unique patient populations with unmet needs. Headquartered in Palo Alto, CA, BridgeBio emphasizes bridging the gap between scientific advancements and patient care.

📋 Description

• Design, execute, and interpret integrative computational analyses spanning multiomics datasets to accelerate therapeutic discovery in rare and genetically defined diseases • Identify opportunities where diverse biological data can answer challenging scientific questions • Generate therapeutic hypotheses and advance biomarker discovery • Leverage AI-enabled computational approaches while applying sound scientific judgment • Contribute to or independently lead computational analyses across diverse disease programs, depending on experience • Analyze and integrate public and internal datasets to generate, prioritize, and refine therapeutic hypotheses • Collaborate with cross-functional scientists to translate computational analyses into actionable scientific insights • Communicate results through presentations, written reports, scientific publications, and conferences

🎯 Requirements

• PhD in Computational Biology, Bioinformatics, Genetics, or a related quantitative discipline • 2+ years of industry and/or postdoctoral experience; 5+ years for Senior level • Experience applying computational methods to large-scale biological datasets • Experience analyzing transcriptomic, proteomic, genetic, and/or related biological datasets • Working proficiency in Python for scientific computing and data analysis • Ability to rapidly learn new disease areas, identify appropriate datasets, and integrate diverse evidence into actionable scientific insights • Excellent communication skills • Ability to thrive as an independent contributor in a collaborative, fast-moving research environment • Preferred: experience supporting biomarker discovery, translational research, or target identification in biotechnology or pharmaceutical settings • Preferred: experience with transcriptomic approaches, particularly single-cell RNA sequencing • Strongly preferred: experience with spatial transcriptomics or related cellular profiling technologies • Preferred: experience using large language models and agentic AI workflows for computational biology research, with scientific validation of outputs • Preferred: deep expertise in at least one area of computational biology while contributing broadly across multiomics analyses

🏖️ Benefits

• Patient Days with opportunities to hear directly from individuals living with impacted conditions • Access to learning and development resources • Market-leading compensation • Performance bonus • Equity • Health, welfare, and retirement programs • Flexible PTO • Rapid career advancement for strong performers • Potential to work on multiple GondolaBio programs across therapeutic areas • Commitment to Diversity, Equity & Inclusion • 401(k) with employer match • Employee Stock Purchase Program (ESPP) • Pre-tax commuter benefits for transit and parking • Referral bonus for hired candidates • Subsidized lunch and parking on in-office days • 100% employer-paid medical, dental, and vision premiums for you and your dependents • Health Savings Account (HSA) with annual employer contributions • Flexible Spending Accounts (FSA) • Fertility and family-forming benefits • Expanded mental health support, including therapy and coaching resources • Hybrid work model with flexibility • Flexible, “take-what-you-need” paid time off and company-paid holidays • Comprehensive paid medical and parental leave • Career pathing through regular feedback, continuous education, and professional development programs via LinkedIn Learning, LifeLabs, and BetterUp Coaching • Financial rewards, peer-to-peer recognition, and growth opportunities

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