Staff Bioinformatics Scientist – Oncology/MRD Algorithm Development

🕒 September 24

🏄 California – Remote

🏄 California – Remote

💵 $155.6k - $233.4k / year

⏰ Full Time

🔴 Lead

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Illumina

WebsiteLinkedInAll Job Openings

5001 - 10000 employees

Founded 1998

🏥 Healthcare

💼 Consulting

🏭 Manufacturing

💰 $750M Post-IPO Debt on 2023-01

Healthcare • Consulting • Manufacturing

Illumina is a leading company in the genomics field, providing innovative technologies for the analysis of genetic variation and function. They offer a wide range of products and services, including sequencing platforms, microarray technology, library preparation kits, bioinformatics software, and comprehensive genomic solutions. Illumina's next-generation sequencing platforms are used for various research and clinical applications, such as cancer research, reproductive health, and genetic disease detection. The company is dedicated to improving human health by enabling researchers and clinicians to accelerate their genomic discoveries and applications, ultimately impacting precision medicine and life sciences globally.

📋 Description

• Drive development of algorithms for detecting minimal residual disease in ctDNA samples using signals from small variant calling, copy number calling, fragmentomics, and methylation • Assist in improving algorithms for therapy selection across a range of variant types and biomarkers • Prototype novel NGS algorithms for clinical oncology use cases such as MRD • Assess and improve existing secondary analysis algorithms for variant and biomarker detection • Design and analyze experiments with external and internal experimental teams to support existing or new Illumina oncology assays • Provide technical guidance to internal and external collaborators • Participate in cross-functional assay and algorithm R&D teams with minimal oversight • Communicate plans and results across functions

🎯 Requirements

• PhD in bioinformatics, computational biology, statistics, math, or related field with 3+ years industry experience • Fluency in at least two of statistics, common bioinformatics methods, NGS analysis, and oncology • Proven track record developing bioinformatics NGS algorithms beyond leveraging existing tools • Fluency in programming languages such as Python • Experience with C++ is desired • Good communication skills to contribute to cross-functional project teams and work with stakeholders • Ability to accommodate meeting times overlapping with Pacific time zone hours • Successful completion of a background check may be required following a conditional offer

🏖️ Benefits

• Variable cash program (bonus or commission) • Equity for eligible roles • Access to genomics sequencing • Family planning benefits • Health, dental, and vision benefits • Retirement benefits • Paid time off • Employee Resource Groups offering career development experiences, cultural awareness, and social responsibility opportunities

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