Senior Clinical Pharmacologist

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🔥 0 minutes ago

🇬🇧 United Kingdom – Remote

⏰ Full Time

🟠 Senior

👻 Ghost score 10%

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ICON plc

WebsiteLinkedInAll Job Openings

10,000+ employees

Founded 1990

💼 Consulting

🏥 Healthcare

📦 Logistics

Consulting • Healthcare • Logistics

ICON plc is a global provider of clinical, consulting, and commercial services across various sectors in the healthcare and pharmaceutical industries. They offer a wide range of clinical solutions, including decentralised clinical trials, cardiac safety solutions, early clinical laboratories, and medical imaging. ICON also provides technology solutions that support drug development from early phases to post-marketing. Their therapeutic expertise spans cardiovascular, oncology, internal medicine, and more, with a strong focus on transformative therapies like cell and gene therapies and biosimilars. ICON is recognized as a leading Contract Research Organisation (CRO), regularly providing thought leadership and contributing to industry publications and events. Their services are tailored to optimize clinical trials, offer regulatory intelligence, and deliver real-world evidence through robust data analysis and patient-centric solutions.

📋 Description

• Lead clinical pharmacology strategies across early and late-phase drug development programs • Apply model-informed drug development principles to support dose selection, patient population strategy, biomarkers, and endpoint optimization • Partner with Pharmacometricians to develop and execute PK/PD modeling and simulation strategies • Contribute to translational medicine initiatives, preclinical study design, and First-in-Human (FIH) studies, including SAD and MAD dose selection • Provide clinical pharmacology expertise to cross-functional teams, governance discussions, and key development decision points • Support regulatory submissions and responses to health authority queries • Drive collaboration across preclinical, clinical, regulatory, and quantitative sciences teams to advance development programs • Stay current with emerging innovations in clinical pharmacology, pharmacokinetics, biopharmaceutics, and quantitative drug development

🎯 Requirements

• PhD in Biological Sciences, Bioengineering, Pharmacology, Pharmaceutical Sciences, or a related discipline • Extensive experience within clinical pharmacology, pharmaceutical development, or a related industry setting • Strong hands-on expertise in clinical pharmacology strategy, study design, PK/PD modelling, and quantitative data interpretation • Deep understanding of model-informed drug development and its application across the drug development lifecycle • Experience supporting translational medicine strategies and early clinical development programs, including FIH studies • Strong knowledge of innovative approaches in clinical pharmacokinetics, biopharmaceutics, and PK/PD modelling • Comprehensive understanding of global drug development and regulatory requirements • Excellent communication and stakeholder management skills, with the ability to influence and build alignment across scientific and business functions • Proven ability to lead complex scientific discussions and contribute to strategic development decisions • Legal right to work in the country where the role is based

🏖️ Benefits

• Competitive base salary and performance related incentives • Health and wellbeing programmes including medical, dental, and vision coverage where applicable • Retirement and pension plans • Life assurance and disability coverage • Employee assistance programmes and wellbeing resources • Learning and development opportunities through structured training and career pathways