
201 - 500 employees
🧬 Biotechnology
🏥 Healthcare
💊 Pharmaceuticals
Biotechnology • Healthcare • Pharmaceuticals
ADC Therapeutics is a commercial-stage global pioneer in the field of antibody drug conjugates (ADCs). The company focuses on transforming the lives of those impacted by cancer through a robust ADC portfolio targeting hematology and solid tumors. Their capabilities include a validated technology platform and a growing research & development toolbox, resulting in an approved product, ZYNLONTA®, for treating diffuse large B-cell lymphoma. Founded in 2011 and based in Lausanne, Switzerland, with operations in London and New Jersey, ADC Therapeutics is committed to confronting cancer and advancing treatment paradigms.
🕒 August 21
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201 - 500 employees
🧬 Biotechnology
🏥 Healthcare
💊 Pharmaceuticals
Biotechnology • Healthcare • Pharmaceuticals
ADC Therapeutics is a commercial-stage global pioneer in the field of antibody drug conjugates (ADCs). The company focuses on transforming the lives of those impacted by cancer through a robust ADC portfolio targeting hematology and solid tumors. Their capabilities include a validated technology platform and a growing research & development toolbox, resulting in an approved product, ZYNLONTA®, for treating diffuse large B-cell lymphoma. Founded in 2011 and based in Lausanne, Switzerland, with operations in London and New Jersey, ADC Therapeutics is committed to confronting cancer and advancing treatment paradigms.
• Serve as the medical monitor for ZYNLONTA studies • Provide real-time clinical judgment on eligibility, dose modifications, premedication compliance, and management of class-specific toxicities • Perform detailed clinical data review of patient data profiles and other eCRF data • Draft data queries and discuss patient cases with Investigators • Lead ongoing benefit-risk assessment, including review of SAEs, AESIs, and emerging safety signals • Partner with Pharmacovigilance, DSMC/iDMC, and Biostatistics for timely signal detection and risk mitigation • Partner with Translational Medicine, Biomarkers, and Biostatistics to characterize patient outcomes • Inform label strategy and lifecycle planning • Ensure medical monitoring and sBLA activities comply with ICH-GCP, FDA/EMA regulations, and internal SOPs • Maintain audit- and inspection-ready documentation of clinical decisions and benefit-risk rationale
• MD required • MD/PhD preferred • Board certification in Hematology/Oncology (in U.S. clinic preferred) • Some clinical experience treating aggressive B-cell lymphomas (DLBCL, HGBCL, transformed FL) strongly preferred • 15+ years of clinical R&D experience in biopharma, or a combination of clinical and industry experience • Direct experience with antibody-drug conjugates (ADCs), particularly PBD-based or CD19-targeted agents • Familiarity with the evolving DLBCL treatment landscape • Ability to position ZYNLONTA strategically within the DLBCL treatment landscape
• Flexible work environment • Approximately 30–40 hours per week remotely
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