Principal Portfolio Project Manager

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🦌 Connecticut, Florida, +8 more states – Remote

🦌 Connecticut – Remote 🐊 Florida – Remote 🦞 Maine – Remote 🏖️ New Jersey – Remote 🌲 North Carolina – Remote 🍂 Massachusetts – Remote 🌴 South Carolina – Remote 🍁 Vermont – Remote ⚔️ Virginia – Remote 🍑 Georgia – Remote

💵 $122k - $196.1k / year

⏰ Full Time

🔴 Lead

👷‍♀️ Project Manager

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Avantor

WebsiteLinkedInAll Job Openings

10,000+ employees

Founded 1904

🏥 Healthcare

🏭 Manufacturing

💼 Consulting

Healthcare • Manufacturing • Consulting

Avantor is a leading life science tools company and global provider of mission-critical products and services to the life sciences and advanced technology industries. The company collaborates with scientists around the world to enable breakthroughs in medicine, healthcare, and technology. Avantor offers a proven portfolio of trusted, quality brands used in research, development, and production activities across more than 300,000 customer locations in 180 countries. It focuses on supporting scientific journeys through reliable products, digital solutions, innovation, and manufacturing facilities. Avantor is committed to sustainability, advancing biopharma, and enhancing scientific collaboration with digital technologies.

📋 Description

• Manage a portfolio of strategic initiatives and capital investments across Engineering, Operations, EHS, PSM, Real Estate, IT, Supply Chain, and Commercial functions • Evaluate, prioritize, and balance project investments based on strategic alignment, business value, risk, resource availability, and organizational capacity • Develop and maintain multi-year portfolio roadmaps • Facilitate portfolio governance reviews, investment decisions, funding approvals, and executive prioritization discussions • Identify portfolio-level risks, dependencies, constraints, and opportunities • Develop executive portfolio dashboards and reporting • Lead multiple concurrent global programs and CAPEX projects • Drive end-to-end project execution from concept through commissioning, qualification, startup, and operational handover • Lead global cross-functional teams without direct reporting authority • Manage projects involving process equipment, assembly systems, manufacturing technologies, automation, and facility infrastructure • Lead facility expansions, process improvements, equipment installations, operational efficiency projects, and capital investment programs • Drive projects through structured stage-gate governance • Prepare and present business cases, project charters, gate reviews, and investment recommendations • Maintain control of project budgets, forecasts, schedules, risks, and financial performance • Manage portfolio-level capital planning, forecasting, cash flow projections, and benefit realization tracking • Develop and manage integrated schedules and mitigate cost and timing risks • Establish KPIs and benefit realization targets; track actual business performance • Manage relationships with contractors, equipment suppliers, engineering firms, consultants, regulatory agencies, and municipalities • Support procurement, vendor selection, contract negotiations, and supplier performance management • Provide direct and indirect leadership to project teams across regions and functions • Mentor and coach project managers and team members • Communicate project, program, and portfolio performance to executive leadership • Drive stakeholder engagement, communication planning, organizational readiness, and adoption activities • Operate autonomously, address complex issues, and make recommendations on investment priorities, resource allocation, and execution strategies • Serve as a subject matter expert and contribute to PMO methodology, governance, and portfolio management improvements

🎯 Requirements

• Bachelor's degree in Engineering, Project Management, Operations, Manufacturing, Business, or related discipline • Minimum of 12 years of progressive project, program, and portfolio management experience, including leadership of global CAPEX projects and strategic business initiatives • Demonstrated success managing large-scale capital projects and cross-functional business programs • PMP certification from the Project Management Institute (PMI), or willingness to obtain within a defined timeframe • Experience in Life Sciences, pharmaceutical, biotech, medical device, specialty chemicals, or similarly regulated industries preferred • Master's degree in Engineering, Business Administration (MBA), Project Management, or related discipline preferred • Proven experience managing portfolios of strategic initiatives and capital investments • Strong understanding of portfolio governance, prioritization methodologies, capital planning, and resource optimization • Ability to balance competing priorities and recommend investments that maximize organizational value • Experience providing executive portfolio reporting and facilitating investment decisions • Strong understanding of business strategy, operations, financial planning, and organizational goals • Ability to translate complex business challenges into executable solutions • Capable of evaluating long-term implications of investment decisions • Extensive knowledge of project management principles and lifecycle methodologies • Proven ability to manage scope, schedule, budget, resources, and risk across global programs • Strong record of delivering large-scale, multi-site CAPEX initiatives • Ability to lead multiple projects and programs simultaneously • Skilled at influencing leaders and teams without direct authority • Trusted advisor to senior stakeholders • Exceptional verbal and written communication skills • Strong presentation and facilitation capabilities • Ability to communicate effectively with executives, business leaders, and technical teams • Strong negotiation and relationship management skills • Experience working with contractors, vendors, engineering firms, regulators, and municipalities • Ability to develop productive partnerships across diverse stakeholder groups

🏖️ Benefits

• Learning experiences to support career growth and success • Diverse, equitable and inclusive culture • Equal employment opportunity protections • Reasonable accommodation during the employment process

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