Senior Biological Data Scientist

🔥 5 minutes ago

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GondolaBio

WebsiteLinkedInAll Job Openings

11 - 50 employees

Founded 2024

🏥 Healthcare

💼 Consulting

🏭 Manufacturing

💰 $300M Venture Round - GondolaBio on 2024-08

Healthcare • Consulting • Manufacturing

GondolaBio is a clinical-stage biopharmaceutical company launched in 2024 and affiliated with BridgeBio Pharma, focused on developing breakthrough therapeutics for patients with genetic diseases. The company uses a lean, decentralized approach to accelerate early-stage research and development across multiple modalities (including small molecules and oligonucleotide therapies) and is building a diverse pipeline targeting rare and underserved genetic conditions such as EPP/XLP with its lead program PORT-77. GondolaBio centers patient needs and aims to bring disease-modifying treatments more quickly to populations lacking approved therapies.

📋 Description

• Design, execute, and interpret integrative computational analyses spanning transcriptomic, proteomic, genetic, and other biological data modalities • Support target identification, biomarker discovery, mechanism-of-action studies, and translational research • Integrate public and internal datasets to generate, prioritize, and refine therapeutic hypotheses across diverse disease programs • Collaborate with cross-functional scientists to translate computational analyses into actionable scientific insights • Communicate results through presentations, written reports, scientific publications, and conferences • Identify opportunities where diverse biological data can answer challenging scientific questions • Generate therapeutic hypotheses and advance biomarker discovery • Leverage AI-enabled computational approaches while applying sound scientific judgment

🎯 Requirements

• PhD in Computational Biology, Bioinformatics, Genetics, or a related quantitative discipline • 5+ years of industry and/or postdoctoral experience applying computational methods to large-scale biological datasets • Demonstrated experience integrating transcriptomic, proteomic, genetic, and related biological datasets • Experience supporting biomarker discovery, translational research, or target identification in a biotechnology or pharmaceutical setting • Working proficiency in Python for scientific computing and data analysis • Ability to rapidly learn new disease areas, identify appropriate datasets, and integrate diverse evidence into actionable scientific insights • Excellent communication skills • Ability to thrive as an independent contributor in a collaborative, fast-moving research environment • Experience with transcriptomic approaches, particularly single-cell RNA sequencing (preferred) • Experience with spatial transcriptomics or related cellular profiling technologies (strongly preferred) • Experience using large language models and agentic AI workflows for computational biology research, with scientific validation of outputs (preferred) • Deep expertise in at least one area of computational biology while contributing broadly across multiomics analyses (preferred) • Periodic travel quarterly or as needed to GondolaBio's Palo Alto office or conference locations

🏖️ Benefits

• Patient Days with opportunities to hear directly from individuals living with relevant conditions • Culture inspired by company values • Decentralized model with reduced bureaucracy and science-focused decision-making • Ownership of program and career vision • Collaborative, fast-paced, data-driven environment • Access to learning and development resources • Robust and market-competitive compensation and benefits package • Performance bonus • Equity • Health and welfare programs • Retirement programs • Flexible PTO • Rapid career advancement for strong performers • Potential ability to work on multiple GondolaBio Pharma programs across multiple therapeutic areas • Commitment to Diversity, Equity & Inclusion