Senior Director, Endometrial Cancer Brand Lead

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Karyopharm Therapeutics Inc.

WebsiteLinkedInAll Job Openings

201 - 500 employees

Founded 2008

💊 Pharmaceuticals

⚕️ Healthcare Insurance

🧬 Biotechnology

Pharmaceuticals • Healthcare Insurance • Biotechnology

Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company dedicated to pioneering novel cancer therapies. Driven by a belief in the extraordinary strength and courage of cancer patients, the company focuses on scientific innovation to develop potentially life-changing treatments for cancers with high unmet medical needs. Karyopharm is at the forefront of Selective Inhibitor of Nuclear Export (SINE) technology, addressing fundamental mechanisms of oncogenesis through ongoing clinical trials for various types of tumors, including hematologic malignancies and solid tumors.

📋 Description

• Own the U.S. EC brand strategy and multi-year commercial roadmap; deliver an annual Brand Plan/AOP with clear objectives, KPIs, milestones, and investment choices aligned to franchise and corporate priorities. • Define and evolve positioning, message platform, and customer value proposition; translate clinical and real-world evidence into differentiated, compliant claims and communications. • Lead lifecycle planning and strategic scenario work (e.g., competitive response, biomarker-driven opportunities, combination strategies, line-of-therapy expansion opportunities, and treatment sequencing dynamics), partnering with cross-functional leaders to evaluate options and trade-offs. • Drive U.S. EC launch strategy and readiness from pivotal data readout through launch execution, defining launch milestones, critical path, and cross-functional workstreams. • Develop customer segmentation and targeting strategy across key stakeholders, including gynecologic oncologists, medical oncologists, academic cancer centers, community oncology practices, integrated delivery networks, and key accounts.

🎯 Requirements

• BS/BA required; advanced degree preferred (MBA, PharmD, PhD, MPH, or equivalent) • 12+ years of commercial biopharmaceutical experience, including 7+ years in oncology marketing • Launch, major lifecycle event, and/or new indication experience in oncology; solid tumor experience preferred • Experience in endometrial cancer, gynecologic oncology, or related oncology markets preferred • Proven success developing brand strategy and delivering commercial results • Strong understanding of U.S. market access, reimbursement, and oncology treatment landscapes • Experience leading cross-functional teams in a fast-paced biotech environment • Exceptional strategic thinking, analytical, communication, and executive presentation skills • Demonstrated ability to influence senior stakeholders and drive alignment across functions

🏖️ Benefits

• medical • dental • vision • 401(k) • and more • equity • potential to receive annual target bonuses