Lead Bioinformatics, Machine Learning Scientist

🔥 0 minutes ago

🇺🇸 United States – Remote

💵 $146k - $182k / year

⏰ Full Time

🟠 Senior

🤖 Machine Learning Engineer

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This company has sponsored H1B visas in the past.

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Natera

WebsiteLinkedInAll Job Openings

1001 - 5000 employees

Founded 2004

🏥 Healthcare

🧬 Biotechnology

⚕️ Healthcare Insurance

Healthcare • Biotechnology • Healthcare Insurance

Natera is a global leader in cell-free DNA testing technology, specializing in non-invasive genetic testing and diagnostics. The company's innovative solutions focus on areas such as prenatal screening, cancer detection, and organ transplant monitoring. By using advanced bioinformatics and DNA analysis, Natera provides healthcare professionals and patients with critical information to make more informed medical decisions.

📋 Description

• Develop, train, and evaluate machine learning models for cancer detection in the minimal residual disease setting • Drive algorithm design decisions supporting cancer detection • Own end-to-end research analyses from ideation through implementation, troubleshooting, and performance evaluation • Develop new features within existing pipelines • Translate between wet-lab experimental design and computational analysis • Maintain rigorous quality control across high-volume sequencing data spanning multiple cohorts, vendors, and clinical protocols • Communicate findings and model performance to technical and cross-functional stakeholders • Contribute to standards for code quality and reproducibility

🎯 Requirements

• PhD in Computer Science, Bioinformatics, Computational Biology, or a related quantitative field with a strong emphasis on cancer epi/genomics • 4 to 8+ years of experience post-PhD • Deep theoretical and practical understanding of high-throughput DNA sequence data analysis, including mapping, sequence alignment, and variant calling workflows • Experience in algorithm development and data analysis, including applying and evaluating statistical methods • Demonstrated experience developing core machine learning models, including generalized linear models, kernel methods, tree-based algorithms, and neural networks, focused on biological data • Strong quantitative reasoning and data analysis skills • Experience with Python and Linux command-line tools, including writing shell scripts • Strong computational and programming skills, including thorough experience with Python statistical packages such as NumPy, Matplotlib, and Pandas • Familiarity with public databases such as TCGA, COSMIC, or OncoKB • Ability to visualize findings and summarize results for technical and non-technical audiences • High scientific rigor and eagerness to learn new computational methods and biology • Ability to work on a cross-functional team with computational and experimental scientists

🏖️ Benefits

• Comprehensive medical, dental, vision, life and disability plans for eligible employees and dependents • Free testing for Natera employees and their immediate families • Fertility care benefits • Pregnancy and baby bonding leave • 401(k) benefits • Commuter benefits • Employee referral program

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