Senior Director, Program Management

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Summit Therapeutics, Inc.

WebsiteLinkedInAll Job Openings

201 - 500 employees

Founded 2003

🧬 Biotechnology

💊 Pharmaceuticals

🔥 Funding within the last year

💰 $500M Post-IPO Equity - Summit Therapeutics on 2025-10

Biotechnology • Pharmaceuticals

Summit Therapeutics, Inc. is a biopharmaceutical oncology company focused on the discovery, development, and commercialization of novel medicinal therapies to improve quality and duration of life for patients with serious unmet medical needs. The company is advancing ivonescimab (SMT112), a novel bispecific antibody targeting PD-1 and VEGF, through multiple Phase 3 clinical trials for non-small cell lung cancer and other solid tumors under license from Akeso. Summit emphasizes clinical development, regulatory filing strategies, and potential commercialization in its licensed territories while promoting patient- and caregiver-friendly treatment options.

📋 Description

• Manage multiple programs or a therapeutic portfolio to maximize pipeline • Partner with executive leadership on program, indication, and portfolio strategy, including prioritization and sequencing • Define and oversee major milestones, decision points, objectives, and inflection points across programs • Lead scenario planning, trade-off analyses, and decision frameworks to support executive decision-making • Ensure alignment across Development, Regulatory, Manufacturing, and Corporate Strategy • Lead and integrate complex cross-functional workstreams across Research, Development, Regulatory, and Manufacturing • Facilitate effective decision-making and accountability across global teams and external partners • Present clear insights, recommendations, and program status to C-suite and senior leadership • Mentor and develop Program Management leaders and strengthen organizational capability • Oversee end-to-end program execution, including activation of new indications post–Go decision • Ensure consistent application of program management standards, dashboards, and governance models • Chair timely, efficient, and action-oriented team meetings to coordinate operations and communications. • Review and validate integrated program plans, timelines, and metrics for accuracy and strategic alignment • Represent Program Management on senior governance forums and key internal or external teams • Oversee integrated, cross-program timelines aligned with enterprise goals • Partner with functional leaders on budgets and forecast planning • Lead portfolio-level scenario and contingency planning to support strategic agility • Ensure data integrity and transparency in executive reporting • Identify and manage program- and portfolio-level risks and mitigation strategies • Communicate risks, opportunities, and trade-offs clearly to executive leadership • Drive continuous improvement of program management processes, tools, and operating models • Lead strategic initiatives to mature the Program Management function as the company grows • All other duties as assigned

🎯 Requirements

• Bachelor’s degree and minimum 15 years of relevant project management/scientific experience within the pharmaceutical industry; OR a MS or MBA and minimal 12 years of relevant experience; OR a PhD in a scientific field or a PharmD, DVM or MD degree with 7+ years of relevant experience • 12–15+ years of pharmaceutical or biotech industry experience with progressive responsibility in program or portfolio management • Extensive pharmaceutical drug development experience required; • Prior solid tumor oncology experience, including late-stage development and registrational trials, required • Demonstrated success leading complex, global, cross-functional programs and influencing senior executives • Experience managing alliances and external partners strongly preferred • Proven ability to balance strategic leadership with operational execution • Exceptional communication, facilitation, and presentation skills • Strong proficiency in program management and planning tools (e.g., MS Office, Project, Smartsheet) • Willing to travel for key meetings.