Senior Bioinformatics Scientist

🕒 July 28

🏄 California – Remote

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💵 $150k - $189k / year

⏰ Full Time

🟠 Senior

👻 Ghost score 25%

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Logo of Veracyte, Inc.

Veracyte, Inc.

501 - 1000 employees

Founded 2013

🏥 Healthcare

🧬 Biotechnology

⚕️ Healthcare Insurance

Healthcare • Biotechnology • Healthcare Insurance

Veracyte, Inc. is a genomic diagnostics company focused on empowering clinicians with high-value molecular tests for diagnosing and treating cancer. The company provides a portfolio of genomic classifiers for various types of cancer, including thyroid, prostate, lung, breast, and bladder cancer, as well as interstitial lung disease. Veracyte's tests help clinicians and patients make informed decisions about cancer care by providing clear diagnostic and prognostic insights. The company's approach involves identifying unmet clinical needs and developing high-performance tests that are widely accessible globally through a CLIA and in vitro diagnostic-based model. Committed to elevating the standard of cancer care, Veracyte continues to expand its test portfolio and make significant contributions to the field of oncology diagnostics.

📋 Description

• Lead bioinformatics design, development, and validation for assay development involving new and on-market products • Coordinate project-core-team planning, execution, and delivery within timelines and budget constraints • Apply bioinformatics, genomics, and assay-technology expertise to achieve assay-development objectives • Drive development-study design and analysis with cross-functional teams • Develop statistical and machine-learning techniques to evaluate assay performance and create optimization strategies • Communicate analyses, methodologies, and scientific findings to internal teams, external collaborators, and stakeholders • Develop scalable production-grade workflows for high-throughput NGS data analysis using AWS and containerized environments • Work with infrastructure and engineering teams to deploy production pipelines • Ensure compliance with CAP/CLIA, FDA, and IVDR standards through testing and documentation • Contribute technical documentation and validation reports to regulatory submissions and audits • Provide scientific guidance and mentorship to junior bioinformatics team members

🎯 Requirements

• PhD or MS in bioinformatics, computational biology, or an adjacent data science field such as biostatistics, statistics, or computer science • Minimum of 6–7 years of experience in bioinformatics analysis, algorithm development, and pipeline implementation • Thorough understanding of NGS technologies and library preparation methods, including WGS, enrichment, RNA-Seq, and methylation • Proficiency in quantitative transcriptomics from NGS or expression microarray data in human disease/biology • Proficiency in machine learning, novel bioinformatics methodologies, algorithm development, and computational-method benchmarking • Proven experience developing and deploying bioinformatics workflows in AWS, including EC2, S3, Step Functions, Batch, and Lambda • Strong proficiency in Python, including testing frameworks and SDLC best practices • Close collaboration with Quality and Regulatory Affairs on assay and analysis pipeline development and verification • Demonstrated technical and scientific leadership, ownership, and independent work • Preferred: experience with wet-lab scientists, variant calling, NGS QC, splicing, circular nucleic acids, germline and somatic mutation processes, TMB, mutational signatures, LOH, R, relational/non-relational databases, data visualizations, technical communication, and troubleshooting

🏖️ Benefits

• Competitive compensation and benefits • Additional discretionary bonuses/incentives may be available • Restricted stock units may be available • Career opportunities and opportunities to learn and grow • Inclusive workforce and workplace • Equal Opportunity Employer

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