Senior Bioinformatics Scientist

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🏄 California – Remote

🏄 California – Remote

💵 $162k - $178k / year

⏰ Full Time

🟠 Senior

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Veracyte, Inc.

WebsiteLinkedInAll Job Openings

501 - 1000 employees

Founded 2013

🧬 Biotechnology

⚕️ Healthcare Insurance

💊 Pharmaceuticals

Biotechnology • Healthcare Insurance • Pharmaceuticals

Veracyte, Inc. is a genomic diagnostics company focused on empowering clinicians with high-value molecular tests for diagnosing and treating cancer. The company provides a portfolio of genomic classifiers for various types of cancer, including thyroid, prostate, lung, breast, and bladder cancer, as well as interstitial lung disease. Veracyte's tests help clinicians and patients make informed decisions about cancer care by providing clear diagnostic and prognostic insights. The company's approach involves identifying unmet clinical needs and developing high-performance tests that are widely accessible globally through a CLIA and in vitro diagnostic-based model. Committed to elevating the standard of cancer care, Veracyte continues to expand its test portfolio and make significant contributions to the field of oncology diagnostics.

📋 Description

• Drive the design, and development of next-generation minimal residual disease (MRD) laboratory-developed tests (LDTs). • Contribute to assay concepts, driving analytical development and validation. • Partner closely with wet-lab, clinical, quality, regulatory, and software teams to deliver robust MRD diagnostics for multiple indications. • Lead technical execution of key scientific efforts, owning assay bioinformatics from concept through analytical validation and launch. • Contribute to bioinformatics strategy for MRD assay design, development, optimization, and lifecycle management for LDTs developed under CAP/CLIA quality systems. • Lead and contribute to study design, data analysis, performance characterization, and decision-making throughout development. • Develop, validate, and maintain scalable, production-ready bioinformatics pipelines for MRD analysis, including QC, variant calling, MRD calling logic, and reporting.

🎯 Requirements

• Ph.D. in Bioinformatics, Computational Biology, Genomics, Biostatistics, or a closely related quantitative field (or M.Sc. plus 3 additional years industry experience). • Minimum 6 years of total relevant experience in biotech, diagnostics, or regulated healthcare environments. • Demonstrated experience in NGS-based assay development for clinical diagnostics. Hands-on experience with ctDNA-based MRD assays, including personalized or tumor-informed approaches. • Strong programming skills in Python, with experience developing reproducible, production-grade analysis pipelines, including experience with SDLC best practices. • Proven experience working in design-controlled, regulated environments (CAP/CLIA LDT, IVD, or equivalent). • Proficiency in development of novel bioinformatics methodologies, and algorithms development, including benchmarking of computational methods. • Track record of working with wet lab scientists on iterative experiment design, execution, analysis, and interpretation as a tightly integrated team. • Demonstrated record of technical and scientific ownership, and independent work.

🏖️ Benefits

• Competitive compensation • Health insurance • Paid time off • Professional development opportunities • Flexible work arrangements