Director, AI Enablement

🕒 May 19

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Apogee Therapeutics

WebsiteLinkedInAll Job Openings

51 - 200 employees

🧬 Biotechnology

💊 Pharmaceuticals

💰 $149M Series B on 2022-12

Biotechnology • Pharmaceuticals

Apogee Therapeutics is a clinical stage biotechnology company focused on developing novel biologics for the treatment of inflammatory and immunology disorders. The company targets major markets in inflammatory and immune diseases such as atopic dermatitis, asthma, chronic obstructive pulmonary disease, eosinophilic esophagitis, and other related conditions. Apogee Therapeutics seeks to reshape the current standard of care by advancing antibody therapeutics that target well-established biological mechanisms, with the potential to address dermatological, respiratory, and gastroenterological issues. The company is committed to creating a psychologically safe workplace while prioritizing innovative treatment options for those living with these conditions.

📋 Description

• Own end-to-end execution of the AI Enablement Program: working group facilitation, use case pipeline management, adoption tracking, and executive reporting • Drive AI literacy and responsible use across a diverse workforce, meeting employees where they are and building capability without coercion • Design and deliver training and engagement programs calibrated to varied audience profiles and functional contexts • Manage the use case intake pathway from submission through scoring, cross-functional review, and outcome documentation • Coordinate with external AI strategy and implementation partners to maintain an integrated, non-duplicative delivery pipeline • Partner with Cybersecurity on AI tool security reviews, access control requirements, audit logging, and risk response protocols • Collaborate with Legal and Compliance on data privacy, IP risk, MNPI controls, and contractual obligations across AI deployments • Work with Data Engineering & Analytics to align AI tools with the enterprise data platform and govern data access across regulated and non-regulated environments • Engage Clinical Operations, Regulatory Affairs, and Medical teams to surface, prioritize, and advance AI use cases in trial and submission workflows • Partner with Finance, HR, Commercial, and G&A leadership on non-clinical use case discovery and deployment • Facilitate the AI Working Group, maintaining cross-functional accountability and structured deliberation on tool assessments and program priorities • Serve as the enterprise administer on the AI and agent tool landscape, owning tool selection, lifecycle management, and the capability roadmap across LLM platforms, agentic workflows, productivity tools, and clinical AI applications • Evaluate net-new tools and agentic frameworks through the governance assessment pathway before deployment; maintain the approved tool inventory with current risk classifications • Manage vendor relationships, contract terms, and licensing decisions in coordination with Finance, Legal, and Procurement • Stay ahead of capability shifts in the agent ecosystem and proactively surface opportunities. • Administer the AI Governance Framework: Approved Systems Registry, risk classification tiers, and GxP and non-GxP assessment pathways • Ensure AI deployments meet applicable regulatory, privacy, and data integrity standards, and support audit readiness across GxP-adjacent environments • Evolve governance controls as the tool landscape and regulatory environment change. • Define and own program success metrics, such as adoption rates, use case throughput, time-to-assessment, literacy baselines, and quantified efficiency gains by function • Establish a reporting cadence to leadership and the Governance Committee with clear narrative on program ROI and risk posture • Maintain a use case outcomes repository to capture lessons learned and identify replication opportunities across the organization • Benchmark Apogee’s AI maturity against clinical-stage biotech peers and industry best practice to prioritize program investments

🎯 Requirements

• 8+ years of progressive experience in digital strategy, enterprise technology, or AI program leadership; prior experience at a life sciences, biotech, or regulated healthcare organization strongly preferred • Demonstrated ability to develop and execute AI or digital strategy in a matrixed, cross-functional environment • Track record of building or operating AI governance, risk classification, or responsible AI frameworks • Proven cross-functional leadership: ability to earn trust and drive outcomes across Cybersecurity, Legal, Clinical, and business functions without formal authority • Hands-on familiarity with enterprise AI platforms, LLM-based tools, and agentic frameworks, including policy administration and access controls • Strong executive communication and presentation skills; ability to advise senior leadership with clarity and appropriate precision • Demonstrated change management capability across organizations with varied adoption readiness • Direct experience in a clinical-stage or late-phase biotech or pharma environment, with working knowledge of GxP, 21 CFR Part 11, Annex 11, or comparable frameworks • Familiarity with agentic AI architectures and multi-tool orchestration in enterprise environments • Consulting background (Big 4 or strategy firm) with experience managing multi-stakeholder programs and external delivery partners • Working knowledge of FDA AI/ML guidance, EU AI Act, or NIST AI RMF as they apply to enterprise or clinical AI deployment

🏖️ Benefits

• A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless • Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly • Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits • We provide competitive time off, including three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave • Commitment to growing you professionally and providing access to resources to further your development • Apogee offers regular all team, in-person meetings to build relationships and problem solve