Senior Director, Market Readiness, Medical Strategy

🔥 57 minutes ago

🏄 California – Remote

🏄 California – Remote

💵 $275k - $305k / year

⏰ Full Time

🟠 Senior

👨‍⚕️ Medical Director

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Atrium Therapeutics

WebsiteLinkedInAll Job Openings

11 - 50 employees

Founded 2026

🧬 Biotechnology

💊 Pharmaceuticals

Biotechnology • Pharmaceuticals

Atrium Therapeutics is a clinical-stage biotechnology company developing precision RNA medicines targeted to the heart. The company has a proprietary RNA delivery platform built on clinically validated AOC (antibody-oligonucleotide conjugate) technology originally designed at Avidity Biosciences, enabling delivery of oligonucleotide therapies directly into cardiac muscle while addressing cytotoxicity, immunogenicity, and redosing limitations. Atrium's pipeline includes lead candidates ATR-1072 for PRKAG2 syndrome and ATR-1086 for PLN cardiomyopathy, plus additional research-stage targets in rare cardiomyopathies; the company plans to file an IND for ATR-1072 in the second half of 2026. Atrium positions itself to pioneer precision cardiology by bringing RNA therapeutics to patients with genetic and rare forms of heart disease.

📋 Description

• Serve as Atrium’s internal subject matter expert on the rare cardiomyopathy disease landscape, anchoring market shaping strategy in deep scientific and clinical understanding, partnering closely with the early development core team to inform trial design and patient identification infrastructure. • Develop and lead patient mapping strategy across relevant cardiomyopathy indications, including genotype-phenotype landscape analysis, patient journey modeling, and identification of underdiagnosed populations • Lead disease awareness and diagnostic gap strategy. • Build and execute a comprehensive KOL engagement strategy spanning academic centers, rare disease specialists, and emerging digital opinion leaders in cardiomyopathy and cardiovascular genetics • Establish and steward advisory board programs, ensuring high-quality scientific exchange and actionable insight generation for internal stakeholders across clinical, R&D, and strategy functions • Maintain a high-integrity external engagement approach aligned with Atrium’s scientific standards and evolving program needs • Collaborate with clinical development and patient advocacy teams to develop real-world evidence strategy and coordinate natural history studies • Own Atrium’s congress presence strategy, identifying priority conferences, shaping scientific storytelling, and coordinating cross-functional execution across posters, presentations, and symposia • Develop and drive Atrium’s publication plan in partnership with clinical and R&D teams, ensuring a coordinated, scientifically rigorous evidence dissemination strategy aligned with program milestones and disease area priorities • Coordinate internal review, authorship planning, and timeline management to support high-quality scientific output • Lead strategic assessments of pipeline opportunities, including disease area prioritization frameworks, unmet need analyses, and new indication evaluations • Serve as a strategic thought partner to the CSO and ELT on portfolio decisions and investment prioritization, synthesizing clinical, scientific, and market signals into clear recommendation • Build and maintain a systematic competitive intelligence capability, tracking the evolving landscape in genetic cardiomyopathies, including emerging programs, pipeline developments, regulatory signals, and scientific trends • Translate competitive insights into strategic implications for Atrium’s positioning and differentiation narrative • Serve as the foundation of a future market readiness and medical strategy function with the expectation of growing into a people leadership role as Atrium scales • Demonstrate strong leadership in a matrixed environment, building trusted partnerships with cross-functional colleagues, with particular close collaboration with the Early Development Lead

🎯 Requirements

• 12+ years of biopharma experience with a strong foundation in Medical Affairs and a demonstrated ability to think and operate with strategic breadth • Experience in rare disease is required; rare cardiomyopathy or cardiovascular genetics experience is a strong plus • Proven track record building KOL networks, driving publication strategy, and leading congress planning • Comfortable operating as an individual contributor in a lean, resource-constrained environment, a builder who creates structure where none exists • Strong cross-functional influencing skills; good collaborator in a matrix organization, able to operate at the intersection of science, strategy, and execution without formal authority • Advanced degree (MD, PharmD, PhD, or MBA) preferred; exceptional candidates with MS and deep rare disease experience will be considered • 50% travel expected

🏖️ Benefits

• Atrium offers competitive compensation and benefits which include stock options & RSUs, as well as a 401(k) with an employer match. • The comprehensive wellness program includes coverage for medical, dental, vision, LTD, and unlimited time off including summer & winter breaks. • A commitment to learning and development which includes a variety of programming internally developed by and for Atrium employees, opportunities for job-specific training offered by industry, and an education reimbursement program.