Senior Data Scientist, Agentic AI Systems

🔥 0 minutes ago

🇺🇸 United States – Remote

💵 $130k - $150k / year

⏰ Full Time

🟠 Senior

📊 Data Scientist

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Axle Informatics

WebsiteLinkedInAll Job Openings

501 - 1000 employees

🧬 Biotechnology

🏥 Healthcare

🔬 Science

Biotechnology • Healthcare • Science

Axle Informatics is a bioscience and information technology company that offers advancements in translational research, health informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we develop and apply research tools and techniques that empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH) by offering the responsiveness of a small business coupled with the experience, breadth, and depth of a large organization.

📋 Description

• Build agentic AI systems for rare disease research workflows, including conversation logic, information-gathering rules, and confirmation steps • Model outputs in Pydantic and use structured output and tool calling so every field is typed, validated, and traceable to its source • Write, version, and regression test prompts for clinical and scientific reasoning tasks • Build evaluation for tasks without a single right answer using golden sets, offline regression suites, and model-based graders • Keep multi-step LLM workflows responsive under load through asynchronous design, concurrency limits, streaming, timeout handling, and failure handling • Log system actions, request identifiers, latency, errors, and reasoning behind automated choices for review • Translate researcher, clinician, and patient-community needs into data models and system behavior • Contribute to manuscripts, conference abstracts, and posters with NIH investigators and receive authorship credit • Own major components from design through deployment • Work directly with NIH program staff, clinical geneticists, and rare disease information specialists • Help set engineering standards for AI application on the team

🎯 Requirements

• Bachelor’s degree in Data Science, Computer Science, Bioinformatics, Biomedical Informatics, or a related field; equivalent professional experience will be considered in place of a degree • Advanced degree preferred • At least 5 years building and operating production software or data systems • At least 2 years shipping LLM-powered applications, including agents, retrieval, or evaluation • Experience with structured output and tool or function calling using typed schemas and validation • Experience evaluating systems without a single right answer using golden sets, offline regression suites, or model-based graders • Ability to own a service end to end, from schema design through deployment and operation • Ability to obtain and maintain a Public Trust Security clearance • Python, FastAPI, Pydantic, and pytest • LLM application engineering, including provider APIs and gateways, prompt and context design, structured generation, tool use, and tracing • PostgreSQL, including embeddings or vector search alongside relational data • Asynchronous and concurrent Python, plus streaming results to a client • Containers and Kubernetes • Git-based collaboration and CI/CD

🏖️ Benefits

• 100% Medical, Dental & Vision Coverage for Employees • Paid Time Off and Paid Holidays • 401K match up to 5% • Educational Benefits for Career Growth • Employee Referral Bonus • Flexible Spending Accounts: Healthcare (FSA), Parking Reimbursement Account (PRK), Dependent Care Assistant Program (DCAP), Transportation Reimbursement Account (TRN)