
51 - 200 employees
🏥 Healthcare
💼 Consulting
🧬 Biotechnology
Healthcare • Consulting • Biotechnology
BBOT is a biotechnology company developing targeted therapies for cancers driven by RAS signaling and PI3Kα. The company focuses on rational drug design to inhibit the active ON state of RAS and to selectively block RAS-driven PI3K activation, aiming at multiple KRAS mutants and novel approaches to maximize target inhibition. BBOT translates decades of RAS biology research into therapeutic candidates intended to improve outcomes for patients with RAS- and PI3Kα-driven tumors.
🔥 12 minutes ago
🇺🇸 United States – Remote
💵 $200k - $250k / year
⏰ Full Time
🔴 Lead
👨⚕️ Medical Director
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51 - 200 employees
🏥 Healthcare
💼 Consulting
🧬 Biotechnology
Healthcare • Consulting • Biotechnology
BBOT is a biotechnology company developing targeted therapies for cancers driven by RAS signaling and PI3Kα. The company focuses on rational drug design to inhibit the active ON state of RAS and to selectively block RAS-driven PI3K activation, aiming at multiple KRAS mutants and novel approaches to maximize target inhibition. BBOT translates decades of RAS biology research into therapeutic candidates intended to improve outcomes for patients with RAS- and PI3Kα-driven tumors.
• Own the long-range clinical supply strategy across BBOT’s oncology programs • Align sourcing, production, and distribution with pipeline priorities • Work with clinical operations, regulatory, and manufacturing to synchronize trial needs and supply timelines • Identify supply risks and develop mitigation plans • Source commercial comparators, including due diligence and vendor coordination • Build and own Excel supply-and-demand models • Run scenario and sensitivity analyses for planning, budget, and resourcing • Maintain the IRT system for supply configuration and tracking • Manage inventory, expiry, and batch traceability across sites and depots • Support clinical supply chain systems setup and configuration, including IRT user acceptance testing and release • Own label creation and prepare clinical supply content for regulatory and submission packages • Support the supply budget and procurement for clinical supplies and services • Ensure regulatory and country-specific compliance • Partner with quality on batch release, QP support, deviation management, and audit readiness • Support supplier selection and qualification and negotiate vendor contracts • Manage manufacturers, packaging providers, and logistics companies to ensure timely, compliant delivery of clinical trial materials
• Bachelor’s degree in Supply Chain Management, Life Sciences, or related field • Minimum 10 years in clinical supply chain in pharma or biotech, with at least 5 years in a lead role • Small/medium-sized biotech experience strongly preferred • In-depth knowledge of clinical trial operations, cGMP/GDP regulations, and global clinical supply chain best practices • Advanced Excel and supply modeling • Ability to forecast and manage supply, inventory, and risk across multiple global oncology trials • Strong negotiation, vendor management, and contract management skills • Outstanding communication, interpersonal, and leadership skills, with the ability to influence at the executive level • Ability to thrive in a fast-paced, growth-stage environment and adapt quickly as priorities change
• Fully remote work environment • Occasional domestic and international travel
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