Director of Commercial Strategy and Operations

🕒 June 17

🇺🇸 United States – Remote

💵 $246.5k - $268k / year

⏰ Full Time

🔴 Lead

⚙️ Operations

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BillionToOne

WebsiteLinkedInAll Job Openings

201 - 500 employees

Founded 2015

🏥 Healthcare

🧬 Biotechnology

⚕️ Healthcare Insurance

💰 $35M Debt Financing on 2022-12

Healthcare • Biotechnology • Healthcare Insurance

BillionToOne is a leading molecular diagnostics company dedicated to advancing disease detection at the molecular level. Their proprietary technology, known as Quantitative Counting Templates (QCTs™), empowers the detection and measurement of tiny DNA fragments at a single base-pair resolution. This technology is a breakthrough in prenatal screening and oncology, enabling accurate risk assessment for fetal genetic conditions and monitoring cancer therapy effectiveness. BillionToOne’s UNITY Screen™ assesses fetal risks using maternal blood samples, making prenatal testing more efficient. The company is committed to enhancing healthcare by making molecular testing more accurate and accessible, evidenced by its recognition as the Diagnostics Company of the Year and significant funding achievements.

📋 Description

• Partner with the VP, Commercial Sales–Prenatal to set strategy, annual plans, and the operating cadence (WBRs, MBRs, QBRs) that drives revenue and account expansion • Lead territory design and quarterly rebalancing for a 250-person field team scaling into new geographies, with dotted-line management of the Salesforce admins who power the data • Own incentive compensation design and quarterly quota setting — building plans that reinforce strategic priorities and stand up to finance and field scrutiny • Direct sales analytics, dashboards, and reporting, working closely with the commercial data science team to turn field activity into insight and insight into action • Use data to go from "what" to "why" — and from "why" to "what we should do about it" — synthesizing tangible recommendations from field performance, deal outcomes, competitive signal, and product launches • Treat AI as a force multiplier — building a function that produces several multiples of the analytical output of a traditional sales ops team • Program-manage the highest-priority cross-functional initiatives — acceleration programs, health system adoption, EMR integration — and liaise to bring field signal into Product, Marketing, and Market Access

🎯 Requirements

• 10+ years across sales strategy, commercial operations, revenue operations, or top-tier management consulting — with material time partnering closely with senior sales leadership • Proven track record designing territories, setting quotas, and building variable comp plans for field sales orgs during rapid growth • Hands-on analytical rigor: you can do data analysis with AI, build a model in Excel, debug a Salesforce report, and present the answer to the VP in the same day • Experience leading high-performing analytical teams, including data scientists or commercial analysts • Excellent communication and executive presence — credible from individual contributor to C-suite • A builder's mindset: high comfort with ambiguity, and the instinct to ship a v1 and iterate.

🏖️ Benefits

• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80% • Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%) • Supplemental fertility benefits coverage • Retirement savings program including a 4% Company match • Increase paid time off with increased tenure • Latest and greatest hardware (laptop, lab equipment, facilities)