Remote Jobs at Candel Therapeutics

Candel Therapeutics

51 - 200 employees

Founded 1999

🧬 Biotechnology

💊 Pharmaceuticals

🏥 Healthcare

Biotechnology • Pharmaceuticals • Healthcare

Candel Therapeutics is a clinical-stage biotechnology company developing off-the-shelf engineered viral immunotherapies for solid tumors. The company advances two genetically modified viral platforms: aglatimagene besadenovec (CAN-2409), an intratumoral adenoviral gene therapy encoding HSV-thymidine kinase used with oral prodrugs to induce immunogenic cell death and CD8+ T cell–mediated anti-tumor immunity; and linoserpaturev (CAN-3110), a replication-competent, Nestin-promoter–controlled oncolytic HSV designed for tumor-specific killing (notably high-grade glioma). Candel reports Phase 3 data for aglatimagene in prostate cancer with strong pathological response rates and has received FDA Fast Track and RMAT designations; it positions itself as an immuno-oncology company focused on improving outcomes and preserving quality of life.