Associate Director of Bioinformatics – Women's Health, Organ Health

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🔥 0 minutes ago

🇺🇸 United States – Remote

💵 $166.6k - $202k / year

⏰ Full Time

🟠 Senior

👔 Director

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Natera

WebsiteLinkedInAll Job Openings

1001 - 5000 employees

Founded 2004

🏥 Healthcare

🧬 Biotechnology

⚕️ Healthcare Insurance

Healthcare • Biotechnology • Healthcare Insurance

Natera is a global leader in cell-free DNA testing technology, specializing in non-invasive genetic testing and diagnostics. The company's innovative solutions focus on areas such as prenatal screening, cancer detection, and organ transplant monitoring. By using advanced bioinformatics and DNA analysis, Natera provides healthcare professionals and patients with critical information to make more informed medical decisions.

📋 Description

• Lead and mentor a team of Bioinformatics Scientists, owning their professional growth, responsibilities, and standards • Own the research strategy for new product development from scoping through execution • Lead bioinformatics analysis for assay development and optimization, troubleshooting experiments with laboratory scientists • Work across methylation, fragmentomics, other cfDNA-derived features, short-read and long-read sequencing, hybrid-capture, and amplicon target enrichment • Partner with laboratory teams on research and feasibility study design, technology assessment, optimization, and performance determination • Improve analysis pipelines for variant detection, quality control, methylation calling, fragment-size and end-motif analysis, error suppression, and structural-variant calling • Move research prototypes into stable production workflows using version control, testing, continuous integration and delivery, and containerization • Automate research data management, pipeline execution, and reporting • Establish standards for appropriate AI-agent-assisted work and scientist sign-off • Collaborate with data science, molecular biology, pipeline engineering, biostatistics, quality assurance, and laboratory operations • Serve as a bioinformatics subject-matter expert and communicate findings and roadmaps across the company • Own the team research roadmap and ensure research methods reach production code and demonstrate expected benchmark performance

🎯 Requirements

• Ph.D. in Bioinformatics, Computational Biology, Computer Science, Mathematics, Engineering, Biostatistics, or a related field; an M.S. with equivalent experience is considered • 7+ years in bioinformatics, including 3+ years leading scientists and working across functions • Demonstrated ownership of a team that took scientific research into real clinical use • Demonstrated experience developing or scientifically guiding diagnostic sequencing assays • Deep expertise in next-generation sequencing analysis, including hybrid-capture or amplicon-based target enrichment, sequencing quality control, secondary analysis, and variant calling • Experience with cell-free DNA sequencing and other omics data, especially in diagnostics • Working knowledge of diagnostic product development in a regulated, accredited setting • Strong Python, programming, and data analysis skills • Fluency in exploratory data analysis and visualization on complex datasets • Ability to translate findings into actionable recommendations • Understanding of sequencing workflows from sample extraction through the instrument • Demonstrated record of assessing a new platform, assay chemistry, or method against established benchmarks • Long-read sequencing, including PacBio HiFi or Oxford Nanopore, in addition to short-read Illumina sequencing • R, shell scripting, or Java • Cloud computing with AWS or GCP and workflow orchestration with Snakemake, WDL, Nextflow, or Cromwell • Containerization with Docker or Kubernetes for reproducible, production-grade analyses • Conference presentations or peer-reviewed publications may be advantageous

🏖️ Benefits

• Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents • Free testing for Natera employees and their immediate families • Fertility care benefits • Pregnancy and baby bonding leave • 401(k) benefits • Commuter benefits • Employee referral program