Director, CAR T Channel Strategy – Operations

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Kyverna Therapeutics

WebsiteLinkedInAll Job Openings

51 - 200 employees

Founded 2019

🧬 Biotechnology

💊 Pharmaceuticals

🔬 Science

💰 $85M Series B on 2022-01

Biotechnology • Pharmaceuticals • Science

Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company focused on developing cell therapies for patients suffering from autoimmune diseases. The company is pioneering CAR T-cell therapies, leveraging the transformational power of T cells to potentially provide sustained, treatment-free remission for autoimmune conditions. Kyverna's lead CAR T-cell therapy candidate, KYV-101, is advancing through clinical trials targeting various autoimmune diseases, including multiple sclerosis, myasthenia gravis, systemic sclerosis, and lupus nephritis. Their pipeline features innovative chimeric antigen receptor (CAR) T-cell therapies in both autologous and allogeneic formats aimed at B cell-driven autoimmune diseases.

📋 Description

• Develop and execute channel strategies that balance customer experience, operational efficiency, compliance requirements, and gross-to-net (GTN) optimization. • Serve as business owner for third-party logistics (3PL) partnerships and distribution operations supporting CAR T commercialization. • Lead specialty pharmacy and distribution strategy development to support current and future portfolio needs. • Partner with Market Access, Finance, Commercial, and Legal teams to evaluate channel design alternatives and their impact on GTN performance. • Assess channel economics and recommend strategies that optimize reimbursement, contracting, distribution costs, and commercial profitability while maintaining customer satisfaction. • Oversee state licensing strategy, renewals, compliance requirements, and regulatory readiness. • Support government pricing activities through cross-functional coordination, process governance, and operational oversight. • Lead distribution governance, service-level management, and operational performance reviews across external partners. • Support launch planning, market expansion, and new product introductions through scalable channel infrastructure. • Develop reporting, analytics, and performance metrics that provide visibility into channel effectiveness and operational health. • Identify and mitigate operational, regulatory, and commercial risks across the distribution network.

🎯 Requirements

• Bachelor’s degree required; advanced degree preferred. • 10+ years of experience in biotechnology, pharmaceutical, specialty distribution, market access, commercial operations, or related functions. • Experience developing and executing channel strategies for specialty pharmaceuticals, cell therapies, gene therapies, or other complex therapies. • Strong understanding of gross-to-net (GTN) principles, channel economics, distribution agreements, and commercial contracting. • Demonstrated ability to design channel solutions that optimize GTN performance while meeting customer, provider, and patient requirements.

🏖️ Benefits

• bonus • benefits • participation in Company’s stock plan