VP, Commercial Operations

🕒 May 16

🏄 California – Remote

🏄 California – Remote

💵 $300k - $340k / year

⏰ Full Time

🔴 Lead

⚙️ Operations

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Kyverna Therapeutics

WebsiteLinkedInAll Job Openings

51 - 200 employees

Founded 2019

🧬 Biotechnology

💊 Pharmaceuticals

🔬 Science

💰 $85M Series B on 2022-01

Biotechnology • Pharmaceuticals • Science

Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company focused on developing cell therapies for patients suffering from autoimmune diseases. The company is pioneering CAR T-cell therapies, leveraging the transformational power of T cells to potentially provide sustained, treatment-free remission for autoimmune conditions. Kyverna's lead CAR T-cell therapy candidate, KYV-101, is advancing through clinical trials targeting various autoimmune diseases, including multiple sclerosis, myasthenia gravis, systemic sclerosis, and lupus nephritis. Their pipeline features innovative chimeric antigen receptor (CAR) T-cell therapies in both autologous and allogeneic formats aimed at B cell-driven autoimmune diseases.

📋 Description

• Build and scale the Commercial Operations function to support pre-commercial through commercial-stage growth. • Partner with Commercial Leadership to develop launch strategies, go-to-market models, field deployment plans, and operational infrastructure. • Lead launch readiness activities including territory alignment, targeting, incentive compensation, CRM implementation, analytics, and reporting. • Develop operational frameworks to support specialty product commercialization, including infused and buy-and-bill reimbursement environments. • Support long-range planning, annual operating planning, and commercial forecasting activities. • Lead all field operations activities including sales force sizing, structure, alignment, targeting, call planning, and performance analytics. • Oversee incentive compensation design, administration, and optimization aligned with business objectives. • Establish KPIs, dashboards, and reporting frameworks to measure commercial effectiveness and drive data-informed decision-making. • Partner with field leadership to optimize execution, productivity, and customer engagement strategies. • Ensure operational excellence across CRM systems, field tools, data governance, and commercial technologies. • Lead forecasting, market analytics, competitive intelligence, and business insights capabilities. • Translate complex market, customer, and performance data into actionable commercial strategic recommendations. • Partner with Market Access and Finance to support pricing, reimbursement, and access planning activities. • Build scalable data infrastructure and reporting capabilities to support executive decision-making. • Drive adoption and optimization of analytics platforms and commercial technologies. • Collaborate closely with Marketing, Sales, Market Access, Medical Affairs, Patient Services, Regulatory, Compliance, and IT to ensure coordinated commercial execution. • Serve as a key strategic advisor to executive leadership on commercialization strategy and operational planning. • Partner with Compliance and Legal to develop Field Compliance SOPs and ensure all commercial activities adhere to regulatory and corporate standards. • Support alliance management and cross-functional governance processes as needed. • Recruit, develop, and lead a high-performing Commercial Operations organization. • Foster a culture of accountability, collaboration, innovation, and continuous improvement. • Mentor and develop team members while building scalable organizational capabilities aligned with company growth.

🎯 Requirements

• Bachelor’s degree required; MBA or advanced degree preferred. • 15+ years of biotechnology or pharmaceutical commercial experience with significant leadership experience in Commercial Operations. • Demonstrated success supporting multiple product launches in specialty therapeutics, oncology, cell therapy, CAR-T, neurology, rare disease, or other complex treatment settings strongly preferred. • Deep expertise in commercial operations including forecasting, analytics, field operations, CRM, incentive compensation, targeting, and reporting. • Strong understanding of specialty pharmacy, infused products, buy-and-bill reimbursement, and complex patient access models preferred. • Experience building commercial infrastructure in emerging or growth-stage biotechnology companies highly preferred. • Proven leadership in cross-functional commercial launch planning and execution. • Strong analytical and strategic thinking capabilities with ability to synthesize multiple data points, assess trends and translate into actionable business insights. • Experience with commercial systems and platforms including CRM, data visualization, incentive compensation, and analytics tools. • Excellent executive presence, communication, and stakeholder management skills. • Demonstrated ability to operate effectively in highly matrixed, fast-paced environments. • Strong people leadership, organizational development, and talent management capabilities. • Ability to travel as needed for commercial meetings, field engagement, conferences, and company activities.

🏖️ Benefits

• Annual bonus • Equity • Benefits • Participation in the Company’s stock plan