Director – Accounting

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🕒 October 24, 2025

🍂 Massachusetts – Remote

🍂 Massachusetts – Remote

💵 $185k - $240k / year

⏰ Full Time

🟠 Senior

🧾 Accounting Manager

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Praxis Precision Medicines, Inc.

WebsiteLinkedInAll Job Openings

51 - 200 employees

🧬 Biotechnology

💊 Pharmaceuticals

Biotechnology • Pharmaceuticals

Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company translating insights from human genetics into the development of precision therapies for central nervous system (CNS) disorders, with a strong focus on genetic epilepsies and neuronal excitation–inhibition imbalance. The company uses genetics-driven target selection, translational tools, patient-guided development, and efficient clinical strategies to advance multiple clinical- and early-stage programs aimed at delivering high-impact treatments for patients with complex brain disorders.

📋 Description

• Responsible for consolidated financial results by overseeing monthly and quarterly financial close processes, including review of key areas of judgment and key general ledger account reconciliations (including R&D accruals) to ensure the accurate and timely preparation of the Company’s consolidated financial statements. • Oversee the Company’s internal financial control compliance (SOX 404(b)), working to strengthen internal controls and ensure the control environment is operating effectively in a dynamic and scaling setting. • Oversight of SEC process, including quarterly and annual reporting, proxy statement and ad-hoc filings. • Responsible for key technical accounting judgments and policies, including oversight, implementation and execution of new accounting guidance. • Collaborate with other G&A teams to ensure relevant information is shared timely, including FP&A, procurement, legal and others as needed. • Build cross-company relationships with key business partners involved in accounting intensive activities to ensure processes are effective and controls are sufficient. • Identify and implement process improvements to continue building the efficiency and effectiveness of accounting at Praxis. • Prepare and present quarterly results presentation and key accounting updates to executive leadership and the Audit Committee. • Support a high performing Accounting team of direct and indirect reports, ensuring all team members remain motivated, challenged through learning opportunities and guided in their professional development.

🎯 Requirements

• Bachelor’s degree in accounting and an active CPA license required • 12+ years of related accounting experience required; public and private experience preferred • Prior employment at a biotech/pharma company required; experience with accounting at a commercial-stage company preferred • Strong knowledge of US GAAP and SOX principles is required • Detail oriented self-starter with ability to think strategically and effectively prioritize while managing various projects simultaneously • Excellent verbal and written communication skills, ability to work collaboratively with other parts of the business including key internal/external stakeholders and executive leadership • Ability to be flexible and continuously drive processes, deliverables, and timelines in a dynamic, fast-paced environment. • Experience working within Agile framework is helpful.

🏖️ Benefits

• 99% premium cost covered for medical (Blue Cross Blue Shield), dental, and vision plans • Bonus program structured to pay on a quarterly basis • 401k plan with 100% match up to 6% of employee’s contribution (Traditional & Roth) • Wellness benefit of $200/month towards incredibly flexible options including travel, fitness equipment & memberships, student loan repayment, sports fees and much more • Unlimited PTO • (2) weeklong shutdowns each year • Generous extended family leave benefit • Eligibility for equity awards and Employee Stock Purchase Plan (15% discount)