
11 - 50 employees
Founded 2026
🧬 Biotechnology
đź’Š Pharmaceuticals
Biotechnology • Pharmaceuticals
Atrium Therapeutics is a clinical-stage biotechnology company developing precision RNA medicines targeted to the heart. The company has a proprietary RNA delivery platform built on clinically validated AOC (antibody-oligonucleotide conjugate) technology originally designed at Avidity Biosciences, enabling delivery of oligonucleotide therapies directly into cardiac muscle while addressing cytotoxicity, immunogenicity, and redosing limitations. Atrium's pipeline includes lead candidates ATR-1072 for PRKAG2 syndrome and ATR-1086 for PLN cardiomyopathy, plus additional research-stage targets in rare cardiomyopathies; the company plans to file an IND for ATR-1072 in the second half of 2026. Atrium positions itself to pioneer precision cardiology by bringing RNA therapeutics to patients with genetic and rare forms of heart disease.
đź•’ September 10
🏄 California – Remote
đź’µ $180.5k - $199.5k / year
⏰ Full Time
đźź Senior
đź”— Supply Chain
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11 - 50 employees
Founded 2026
🧬 Biotechnology
đź’Š Pharmaceuticals
Biotechnology • Pharmaceuticals
Atrium Therapeutics is a clinical-stage biotechnology company developing precision RNA medicines targeted to the heart. The company has a proprietary RNA delivery platform built on clinically validated AOC (antibody-oligonucleotide conjugate) technology originally designed at Avidity Biosciences, enabling delivery of oligonucleotide therapies directly into cardiac muscle while addressing cytotoxicity, immunogenicity, and redosing limitations. Atrium's pipeline includes lead candidates ATR-1072 for PRKAG2 syndrome and ATR-1086 for PLN cardiomyopathy, plus additional research-stage targets in rare cardiomyopathies; the company plans to file an IND for ATR-1072 in the second half of 2026. Atrium positions itself to pioneer precision cardiology by bringing RNA therapeutics to patients with genetic and rare forms of heart disease.
• Provide strategic direction for clinical supply strategies and create actionable clinical supply plans • Manage IRT/RTSM vendors, specification gathering, user acceptance testing, and IRT lifecycle • Ensure accurate randomization, resupply, and inventory levels across studies and sites • Identify and mitigate clinical supply risks and build contingency plans • Align clinical supply timelines with study start-up, enrollment, and closeout milestones • Oversee packaging, labeling, distribution, and return drug management with CMOs • Represent Clinical Supply Chain in cross-functional study team, CRO, and vendor meetings • Author pharmacy manuals and participate in study-document reviews • Own shipping and logistics requests for GMP and non-GMP materials across technical and scientific teams • Manage couriers, freight forwarders, and specialty cold-chain carriers • Own import/export compliance, licenses, permits, customs documentation, and country-specific import requirements • Oversee cold-chain shipment execution, packaging qualification, temperature excursion investigations, and corrective actions • Monitor shipment status, coordinate inbound/outbound logistics, resolve delays or exceptions, and maintain tracking/reporting • Ensure compliance with GMP, GCP, and applicable import/export regulations • Maintain inspection-ready documentation and file records in eTMF/quality systems • Support SOP creation and revision • Lead or contribute to deviation, CAPA, and investigation processes related to supply or shipping issues
• Bachelor's degree in life sciences, supply chain, logistics, or a related field required; advanced degree preferred • Associate Director: typically 10+ years of clinical supply chain experience in biotech/pharma • Direct experience in packaging, labeling, and distribution of investigational products through all stages of international clinical studies • Experience managing shipping, logistics, or distribution operations, including carrier/freight-forwarder management and import/export or customs compliance • Experience with IRT/RTSM systems, clinical supply forecasting tools, and CMO/depot network management • Experience in rare disease, cardiology, or genetic medicine clinical trials is a plus • Working knowledge of GMP, GCP, and global import/export regulations relevant to clinical trial materials • Strong vendor management, negotiation, and cross-functional collaboration skills • Ability to manage multiple competing priorities in a fast-paced, growing biotech environment • Excellent analytical, organizational, and written/verbal communication skills • Comfort operating with the autonomy and hands-on scope typical of a small, growing company • Some domestic and/or international travel may be required to support vendor, depot, or CMO site visits • Role based in San Diego, CA or remote
• Stock options & RSUs • 401(k) with employer match • Medical coverage • Dental coverage • Vision coverage • LTD coverage • Unlimited time off, including summer & winter breaks • Learning and development programming • Job-specific industry training opportunities • Education reimbursement program
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