Director, Global Value and Health Economics, Outcomes Research

🔥 17 hours ago

🔔 Pennsylvania – Remote

🔔 Pennsylvania – Remote

💵 $212k - $318k / year

⏰ Full Time

🔴 Lead

👔 Director

🦅 H1B Visa Sponsor

This company has sponsored H1B visas in the past.

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Jazz Pharmaceuticals

WebsiteLinkedInAll Job Openings

1001 - 5000 employees

Founded 2003

🏥 Healthcare

🏭 Manufacturing

🧬 Biotechnology

Healthcare • Manufacturing • Biotechnology

Jazz Pharmaceuticals is a biopharmaceutical company dedicated to developing innovative medicines that address serious unmet medical needs. With a strong commitment to research and development, Jazz focuses on creating life-changing therapies, emphasizing the importance of collaboration, diversity, and employee engagement in its operations. The company prides itself on transforming patients' lives through its meaningful product offerings and a culture that fosters enthusiasm and flexibility.

📋 Description

• Define and drive global and US payer evidence strategy for pipeline assets from early clinical development through regulatory approval and launch • Lead global payer evidence generation while serving as the US HEOR lead • Lead US pre-launch HEOR deliverables, payer field enablement tools, and US market access evidence strategies • Translate target product profiles and access ambitions into evidence generation programs, including economic models, natural history studies, Global Value Dossiers, and US AMCP dossiers • Partner with Clinical Development, Biostatistics, and Clinical Operations to integrate payer, formulary, and HTA requirements into Phase 2/3 trial designs • Optimize trial protocols through comparator, inclusion/exclusion criteria, treatment-line, and endpoint recommendations • Integrate PROs, HRQoL, symptom burden scales, and HCRU instruments into pivotal trials • Design rare-disease evidence strategies using natural history data, biomarkers, and external or historical comparators • Architect and lead health economic modeling strategies, including CEAs, BIMs, early conceptual models, and threshold analyses • Direct the design, build, and validation of adaptable global core economic models • Develop US pre-launch evidence roadmaps and lead AMCP PIE dossiers, burden-of-illness dossiers, and US budget impact models • Design payer-facing economic models, evidence decks, and population health tools • Lead HEOR workstreams within Launch Readiness Teams and oversee global launch assets such as GVDs and SLRs • Co-develop EU/INT HTA strategies and analytic packages including ITCs, NMAs, and country model adaptations • Design and execute pre-launch real-world studies, chart reviews, registries, and burden-of-illness evaluations • Serve as a GVHEOR stakeholder in IEGP governance and formulate payer evidence strategies • Develop scientific publication plans, co-author manuscripts, and present findings at major congresses • Mentor junior HEOR scientists, post-doctoral fellows, and matrix colleagues

🎯 Requirements

• Required Master’s degree (MSc, MS, MPH, PhD) in Health Economics, Outcomes Research, Pharmacoeconomics, or a closely related quantitative field • Minimum of 7–10 years of experience in HEOR, Global Value, or Health Economics within the biopharmaceutical industry or a top-tier HEOR consulting firm • Proven track record collaborating with Clinical Development, Commercial Development, and Biostatistics teams to influence Phase 2/3 trial design, comparator choice, trial-based resource use collection, and PRO/HRQoL endpoint selection • Strong familiarity with the US managed care and market access landscape, including commercial payers, Medicare Advantage, Medicare Part D/B, Medicaid, and PBMs • Deep understanding of global HTA frameworks, including EU HTA Regulation/JCA, NICE, G-BA, PBAC, and CADTH • Demonstrated capability to lead HEOR launch-readiness workstreams and deliver GVDs, AMCP PIE dossiers, and global ITCs/NMAs under tight regulatory filing timelines • In-depth knowledge of rare disease drug development evidentiary challenges, including natural history studies, registries, surrogate-to-clinical endpoint translation, external control arms, and specialized HTA pathways • Proven ability to define strategic vision and execute and quality-check complex technical models, statistical analysis plans, and dossier sections • Demonstrated success collaborating with regional HEOR teams, particularly EU/INT teams • Ability to influence cross-functional peers and senior leadership across Clinical Development, Medical Affairs, Market Access, and Commercial without formal authority • Exceptional written and verbal communication skills, with an established record of HEOR and clinical publications in peer-reviewed medical and economic journals, or HTA success • Direct experience leading HEOR strategy and deliverables for pipeline assets, including early Phase 2/3 clinical trial protocol integration, endpoint development, and global launch readiness • Experience managing regional trade-offs on evidence needs as part of Phase 2/3 protocol development • Launch lead for at least 2 assets as US HEOR lead or country-level HTA lead • Hands-on experience designing, overseeing, or adapting health economic models • Experience collaborating with regional HEOR teams to deliver evidence packages supporting HTA readiness and submissions

🏖️ Benefits

• Discretionary annual cash bonus or incentive compensation • Discretionary equity grants • Medical insurance • Dental insurance • Vision insurance • 401k retirement savings plan • Flexible paid vacation

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