Director, Global Value and Health Economics – Outcomes Research

🔥 17 hours ago

🔔 Pennsylvania – Remote

🔔 Pennsylvania – Remote

💵 $212k - $318k / year

⏰ Full Time

🔴 Lead

👔 Director

🦅 H1B Visa Sponsor

This company has sponsored H1B visas in the past.

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Jazz Pharmaceuticals

WebsiteLinkedInAll Job Openings

1001 - 5000 employees

Founded 2003

🏥 Healthcare

🏭 Manufacturing

🧬 Biotechnology

Healthcare • Manufacturing • Biotechnology

Jazz Pharmaceuticals is a biopharmaceutical company dedicated to developing innovative medicines that address serious unmet medical needs. With a strong commitment to research and development, Jazz focuses on creating life-changing therapies, emphasizing the importance of collaboration, diversity, and employee engagement in its operations. The company prides itself on transforming patients' lives through its meaningful product offerings and a culture that fosters enthusiasm and flexibility.

📋 Description

• Lead global and US payer evidence strategy across marketed assets in Jazz’s neurology portfolio • Maximize brand potential, defend product value, secure expanded access, and drive post-launch evidence generation • Lead HEOR evidence strategies for supplemental regulatory filings, new indications, line extensions, expanded populations, and novel formulations/devices • Partner with Medical Affairs, Clinical Development, and Biostatistics on Phase 3b/4 trials, pragmatic studies, PROs, and HRQoL measures • Develop indication sequencing and access strategies with Market Access • Collaborate on rare disease registries, natural history extensions, and post-authorization safety/efficacy studies • Design comparative effectiveness, adherence, and burden-of-illness studies to defend product differentiation • Co-create HTA reassessment strategies and analytical packages with EU/INT HEOR teams • Direct updates to Global Value Dossiers, systematic literature reviews, and meta-analyses • Serve as designated US HEOR expert for assigned inline products • Lead AMCP dossiers, unbranded value summaries, and state Medicaid submission dossiers • Develop and train teams on interactive economic models and reactive scientific presentations • Ensure US HEOR materials comply with FDAMA Section 114, the 21st Century Cures Act, and FDA HCEI guidance • Evaluate outcomes-based risk-sharing agreements and establish real-world endpoint tracking frameworks • Monitor US health policy and prepare evidence plans for ICER and other value assessment bodies • Build and adapt cost-effectiveness, cost-utility, budget impact, cost-offset, Markov, partitioned survival, microsimulation, and dynamic budget impact models • Represent GVHEOR in IEGP governance and align post-marketing studies with brand objectives • Drive post-marketing HEOR publications and present findings at scientific congresses • Manage budgets, external HEOR consultancies, academic partners, and CROs • Mentor associate directors, managers, and fellows

🎯 Requirements

• Master’s degree (MSc, MS, MPH) or PhD in Health Economics, Outcomes Research, Pharmacoeconomics, or a closely related quantitative field • Minimum of 7–10 years of experience in HEOR, Global Value, or Health Economics within the biopharmaceutical industry or a top-tier HEOR consulting firm • Extensive experience designing and executing post-marketing HEOR strategies, real-world comparative effectiveness studies, and evidence roadmaps supporting label expansions, line extensions, and value defense • Comprehensive working knowledge of the US managed care landscape and global HTA environments • Proven technical expertise building, adapting, and validating economic models, including Markov, partitioned survival, microsimulation, and dynamic budget impact models • Proven track record collaborating with US Market Access, Pricing/Contracting, and Payer Field Teams to develop compliant customer-facing tools, interactive budget models, and AMCP dossiers • Demonstrated understanding of rare disease/orphan product post-launch evidence challenges • Working knowledge of major US and global healthcare databases, including IQVIA, Optum, MarketScan, Medicare SAF, disease-specific registries, and electronic health records • Advanced epidemiological methods for comparative research • Demonstrated ability to work with regional HEOR teams, especially EU/INT • Ability to execute complex technical deliverables including dossiers, models, observational research protocols, and publications • Exceptional verbal, written, and presentation skills • Required launch leadership for at least 2 assets as US HEOR lead or country-level HTA lead • Proven track record leading HEOR strategy and executing evidence deliverables for marketed pharmaceutical products • Experience conducting post-marketing RWE, patient registry studies, and economic evaluations in rare diseases, specialized medicine, or complex chronic conditions • Strong peer-reviewed publication record in health economics and outcomes research • Experience with oncology assets preferred

🏖️ Benefits

• Discretionary annual cash bonus or incentive compensation • Discretionary equity grants through the Long Term Equity Incentive Plan • Medical insurance • Dental insurance • Vision insurance • 401k retirement savings plan • Flexible paid vacation

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