Chief of Staff – VC Backed Startups

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SignalFire

WebsiteLinkedInAll Job Openings

11 - 50 employees

Founded 2012

🏥 Healthcare

💼 Consulting

📦 Logistics

Healthcare • Consulting • Logistics

SignalFire is a venture capital firm built on technology and data, dedicated to supporting growth for early-stage companies through advanced AI tools and seasoned sector expertise. They focus on providing unparalleled support to their portfolio companies, combining in-house AI capabilities with tailored advisory programs across multiple sectors such as healthcare, fintech, cybersecurity, and more.

📋 Description

• Partner with the CEO, founder, or executive team on company priorities, strategic planning, and decision-making • Drive high-priority, cross-functional initiatives from problem definition through execution • Establish and manage operating rhythms, including leadership meetings, goal-setting, planning, and business reviews • Prepare executive communications, board materials, investor updates, and strategic presentations • Conduct research and analysis supporting growth, organizational design, product strategy, market expansion, and fundraising decisions • Track company goals, KPIs, and critical initiatives to ensure accountability and follow-through • Identify operational gaps and build processes, systems, and workflows to improve organizational effectiveness • Facilitate cross-functional alignment and resolve issues spanning multiple teams • Support fundraising, annual planning, partnerships, hiring, acquisitions, and new market launches • Serve as a trusted thought partner to the CEO or executive team while maintaining discretion and sound judgment • Join SignalFire’s Talent Network for potential matching with Chief of Staff and strategic operations opportunities at portfolio companies

🎯 Requirements

• 5+ years of experience in strategy, operations, consulting, finance, product, business operations, or a related function • Prior experience in a venture-backed startup, high-growth technology company, consulting firm, investment firm, or similarly fast-paced environment • Demonstrated success leading complex, cross-functional projects with multiple stakeholders • Strong analytical skills and ability to turn incomplete information into structured recommendations • Excellent written and verbal communication skills, including executive-level materials experience • Strong organizational skills and ability to manage competing priorities • High judgment, discretion, and comfort handling sensitive company information • Low-ego, hands-on operating style and willingness to take ownership beyond a defined job description • Experience working directly with a founder, CEO, or executive leadership team is strongly preferred • Background in finance, consulting, investing, business operations, or product strategy may be helpful • Experience with relevant tools such as Excel, Google Sheets, Looker, Tableau, Mode, Notion, Asana, Linear, Monday.com, Airtable, Slack, Google Workspace, Zoom, Microsoft Office, Carta, Ramp, Brex, Mosaic, Pigment, Salesforce, HubSpot, or Gong

🏖️ Benefits

• Estimated OTE of $250K–$300K • Equity offered • Potential access to opportunities across SignalFire’s portfolio companies • Profile kept on file for future Chief of Staff and strategic operations roles