Director, Pharmacometrics – Pop PK, PK/PD

🕒 July 30

🇺🇸 United States – Remote

💵 $180k - $210k / year

⏰ Full Time

🔴 Lead

👔 Director

👻 Ghost score 9%

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Simulations Plus, Inc.

WebsiteLinkedInAll Job Openings

201 - 500 employees

Founded 1996

💊 Pharmaceuticals

🧬 Biotechnology

☁️ SaaS

💰 Grant - Simulations Plus on 2024-11

Pharmaceuticals • Biotechnology • SaaS

Simulations Plus, Inc. is a science-driven software and consulting company that provides mechanistic modeling, AI-enabled workflows, and expert services to support model‑informed drug development (MIDD) across discovery, development, clinical operations, and commercialization. Its product suite includes GastroPlus (PBPK/PBBM), MonolixSuite (pharmacometrics), ADMET Predictor (ML for ADMET), DILIsym (quantitative systems toxicology), Thales (QSP), and Pro‑ficiency (learning/simulation), and the company offers consulting, training, regulatory strategy support, and bundled solution packages. Simulations Plus emphasizes mechanistic and AI-enabled tools for ADMET prediction, PBPK, pharmacometrics, QSP/QST and serves pharmaceutical and biotech clients (noting ~30+ years in business, ~280+ clients and use by 19 of the top 20 pharma companies).

📋 Description

• Independently develop and evaluate complex models and simulations • Lead, manage, and collaborate effectively with cross-functional project teams to successfully support client requests • Build partnerships with clients; provide strategic input and advice • Provide strategic direction regarding the integration of modeling and simulation results and findings • Assist in teaching workshops and providing training • Mentor junior level scientists; may supervise assigned scientists • Promote software and consulting service offerings; may assist in developing proposals and work scopes • Serve as main point of contact for assigned clients and projects • Consult with clients on study design through development and evaluation of models • Clearly communicate and present modeling and simulation results to clients • Use state-of-the-art software to develop, evaluate and apply PK, PK/PD and exposure-response models • Perform model-based simulations to address critical development questions • Write pharmacometric reports and regulatory documents • Share scientific knowledge and skills with other staff members

🎯 Requirements

• 10+ years of population PK and PK/PD modeling experience preferred • Proficiency in Monolix, NONMEM, and R • Professional experience in application of Pharmacometrics to Clinical Pharmacology • Proficient at developing and delivering presentations • Highly self-motivated and willing to take on challenges • Possess excellent critical-thinking, problem-solving, and interpersonal skills • Strong verbal and written communication • Some travel required for meetings, trainings, and conferences

🏖️ Benefits

• fully remote work • flexible schedules • generous vacation policy • affordable health coverage • annual bonus

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