Senior Full-Stack Engineer

🔥 0 minutes ago

🇺🇸 United States – Remote

💵 $90k - $110k / year

⏰ Full Time

🟠 Senior

🧑‍💻 Full-stack Engineer

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Simulations Plus, Inc.

WebsiteLinkedInAll Job Openings

201 - 500 employees

Founded 1996

💊 Pharmaceuticals

🧬 Biotechnology

☁️ SaaS

💰 Grant - Simulations Plus on 2024-11

Pharmaceuticals • Biotechnology • SaaS

Simulations Plus, Inc. is a science-driven software and consulting company that provides mechanistic modeling, AI-enabled workflows, and expert services to support model‑informed drug development (MIDD) across discovery, development, clinical operations, and commercialization. Its product suite includes GastroPlus (PBPK/PBBM), MonolixSuite (pharmacometrics), ADMET Predictor (ML for ADMET), DILIsym (quantitative systems toxicology), Thales (QSP), and Pro‑ficiency (learning/simulation), and the company offers consulting, training, regulatory strategy support, and bundled solution packages. Simulations Plus emphasizes mechanistic and AI-enabled tools for ADMET prediction, PBPK, pharmacometrics, QSP/QST and serves pharmaceutical and biotech clients (noting ~30+ years in business, ~280+ clients and use by 19 of the top 20 pharma companies).

📋 Description

• Own features end-to-end across Node.js and Express backends and React/Tailwind frontends • Build APIs, user interfaces, and data flows behind customer-facing functionality • Contribute to the platform's data, authentication, and service patterns • Integrate LLM-powered functionality into product surfaces alongside the AI lead • Connect frontends to LLM and MCP endpoints • Handle streaming, errors, and degraded states gracefully • Contribute to evaluations, fixtures, and tooling supporting AI development • Bring full-stack range across backend, frontend, and AI work • Contribute to code reviews, documentation, and shared engineering practices • Apply AI coding tools effectively in the daily engineering workflow • Perform other duties as assigned

🎯 Requirements

• 3+ years of professional software engineering experience, with shipped full-stack work in production • Proficiency in JavaScript or TypeScript across Node.js backend and React frontend • Practical experience with document or NoSQL databases such as MongoDB • Comfort building and consuming REST APIs and JSON contracts • Genuine interest in agents, MCP, and applied AI, and the drive to build real expertise in those areas • Fluency using AI coding tools (Claude, Cursor, Copilot) in daily workflow • Familiarity with Anthropic, OpenAI, or other LLM provider SDKs • Exposure to MCP, agent frameworks, or LLM-integrated product features • Experience with cloud infrastructure (AWS preferred) and CI/CD pipelines • Experience in regulated-software environments (SOC 2, HIPAA, GxP, 21 CFR Part 11) or life-sciences SaaS • Familiarity with Passport, OAuth, OIDC, or comparable auth patterns • Bachelor's degree in computer science, engineering, or related field preferred • Relevant technical certifications welcomed

🏖️ Benefits

• Fully remote work • Flexible schedules • Generous vacation policy • Affordable health coverage • Annual bonus