
11 - 50 employees
Founded 2024
🤖 Artificial Intelligence
🔬 Science
☁️ SaaS
Artificial Intelligence • Science • SaaS
FirstPrinciples is a research company building AI systems for discovery in fundamental science. It develops domain-specialized models and tools (branded Theo: Theo Collaborator, Theo Conjecture, and Theo, the AI Physicist) to assist the scientific process—hypothesis generation, symbolic reasoning, tool integration, validation loops, and reproducible research objects. The company emphasizes transparency, stewardship of knowledge as a public good, and alignment with the scientific community. Technical claims include multiple fine-tuned models across physics domains, a model family with 120B+ parameters trained on a curated corpus of 3M+ scientific papers, and internal experiments in areas like quantum information.
🔥 12 hours ago
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11 - 50 employees
Founded 2024
🤖 Artificial Intelligence
🔬 Science
☁️ SaaS
Artificial Intelligence • Science • SaaS
FirstPrinciples is a research company building AI systems for discovery in fundamental science. It develops domain-specialized models and tools (branded Theo: Theo Collaborator, Theo Conjecture, and Theo, the AI Physicist) to assist the scientific process—hypothesis generation, symbolic reasoning, tool integration, validation loops, and reproducible research objects. The company emphasizes transparency, stewardship of knowledge as a public good, and alignment with the scientific community. Technical claims include multiple fine-tuned models across physics domains, a model family with 120B+ parameters trained on a curated corpus of 3M+ scientific papers, and internal experiments in areas like quantum information.
• Partner with research leads to define research programs, priorities, hypotheses, milestones, and expected outcomes • Operationalize and steward the Research Portfolio & ROI Framework • Assess research bets by ambition, uncertainty, impact, maturity, time horizon, confidence, cost, and product applicability • Establish stage-appropriate evidence plans, KPIs, and leading and lagging indicators • Create operating rhythms including regular reviews, clear owners, intermediate deliverables, decision points, and follow-through • Track research initiatives against objectives and investment while preserving room for scientific exploration • Identify stalled projects, weak assumptions, and diminishing returns early • Drive decisions to iterate, redirect, pause, or stop work • Connect research priorities to company, product, and technical strategy • Translate research progress into decisions, implications, and tradeoffs for Product, Engineering, and leadership • Help successful research transition into product capabilities, assets, or future strategic options
• 5+ years as a product manager or program manager in technology or research organizations • Comfortable operating in highly technical, ambiguous, and exploratory environments • Bachelor's degree in computer science, engineering, or related technical field • Deep understanding of program management craft and practices • Ability to guide ambiguous technical programs, make evidence-based decisions under uncertainty, and apply product thinking without constraining scientific exploration • Strong bias toward action and learning velocity • Comfortable holding highly technical teams accountable for commitments, decisions, and outcomes • Strong written and verbal communication skills • Comfort working in a fast-paced startup environment with a remote-first team • Motivated by building a research culture combining scientific ambition with urgency, focus, accountability, and rapid learning
• Remote-first work with flexibility in how you structure your day • High-trust, low-bureaucracy environment with real ownership • Exposure to cutting-edge ideas across AI, scientific discovery, and emerging technologies • Opportunity to work on foundational problems at the intersection of AI and physics • Culture that values curiosity, depth of thinking, and first-principles reasoning • Chance to contribute to work aimed at advancing fundamental science
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