BBOT
51 - 200 employees
🧬 Biotechnology
💊 Pharmaceuticals
Biotechnology • Pharmaceuticals
BBOT is a biotechnology company developing targeted therapies for cancers driven by RAS signaling and PI3Kα. The company focuses on rational drug design to inhibit the active ON state of RAS and to selectively block RAS-driven PI3K activation, aiming at multiple KRAS mutants and novel approaches to maximize target inhibition. BBOT translates decades of RAS biology research into therapeutic candidates intended to improve outcomes for patients with RAS- and PI3Kα-driven tumors.
AD/Director, Toxicology
Job not on LinkedIn
🕒 February 25
🗣️🇨🇳 Chinese Required
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BBOT
51 - 200 employees
🧬 Biotechnology
💊 Pharmaceuticals
Biotechnology • Pharmaceuticals
BBOT is a biotechnology company developing targeted therapies for cancers driven by RAS signaling and PI3Kα. The company focuses on rational drug design to inhibit the active ON state of RAS and to selectively block RAS-driven PI3K activation, aiming at multiple KRAS mutants and novel approaches to maximize target inhibition. BBOT translates decades of RAS biology research into therapeutic candidates intended to improve outcomes for patients with RAS- and PI3Kα-driven tumors.
📋 Description
• Lead and own all in vitro and in vivo non-clinical toxicology activities (non-GLP & GLP) for multiple programs • Design and communicate customized toxicology strategies for each program • Attend program meetings, collaborate with cross-functional team leads, and guide project team leaders regarding toxicology and safety plans and timelines • Plan, design, and oversee the execution of all outsourced CRO collaborations for toxicology and safety studies • Manage, edit, and finalize collaborators’ (CRO) study reports • Analyze, interpret, present, and communicate all preclinical toxicology and safety study findings • Make key recommendations to project teams for mitigation strategies and next steps • Author high-quality regulatory documents to support filings such as IND, CTA, NDA, and IB
🎯 Requirements
• Ph.D. in Toxicology, Pharmacology, Biology, or a related field; DABT preferred but not required • 5+ years of professional experience in toxicology research or drug development in an industry setting; small molecule experience required • Experience working with CROs in the US, Canada, EU, and Asia • Professional level proficiency speaking English is required • Professional level proficiency speaking Chinese is preferred
🏖️ Benefits
• Competitive salary, benefits, and meaningful equity participation in a public company • Annual bonus • Stock-based long-term incentives • Medical, dental, and vision benefits • Retirement • Wellness stipend • Flexible time off
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