Principal Software Engineer

🔥 12 hours ago

🇺🇸 United States – Remote

⏰ Full Time

🔴 Lead

🧑‍💻 Full-stack Engineer

👻 Ghost score 10%

What it means: how likely this posting is sitting open without active hiring.How to read it: 60% or higher means we think this is a ghost. Lower scores are less of a worry.How we score it: age, reposts, open roles vs team size, how fast jobs close, and whether pay is listed.Fine print: an estimate from public data, not a judgment of the company. Real jobs can score high, so treat it as a hint, not a fact.

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Baylor Genetics

WebsiteLinkedInAll Job Openings

501 - 1000 employees

Founded 1978

🏥 Healthcare

💼 Consulting

🍽️ Food & Beverage

Healthcare • Consulting • Food & Beverage

Baylor Genetics is a clinical genomics and precision diagnostics laboratory affiliated with Baylor College of Medicine that provides comprehensive genetic testing and interpretation services. The company offers whole genome and whole exome sequencing, chromosomal microarray analysis, mitochondrial testing, pharmacogenomics, and specialized assays, along with genetic counseling, provider support, and insurance/payment resources. Baylor Genetics supports healthcare providers, researchers, and families with AI-enhanced interpretation, multimodal data integration, and end-to-end clinical and laboratory services.

📋 Description

• Lead the architecture, design, and development of complex software systems and platforms • Define and champion engineering standards, best practices, and long-term technical roadmaps • Collaborate with cross-functional teams to translate business needs into scalable, secure, and maintainable solutions • Conduct deep technical reviews and guide system design discussions • Ensure architectural consistency across teams • Mentor and coach engineers, fostering technical excellence and continuous learning • Drive root-cause analysis and resolution of complex technical issues • Ensure system reliability and data integrity • Evaluate emerging technologies and guide strategic adoption • Partner with product, laboratory, and bioinformatics teams to optimize workflows and operational efficiency • Ensure compliance with security, privacy, and regulatory requirements • Contribute to innovation initiatives advancing Baylor Genetics’ digital capabilities and competitive advantage • Perform other duties as assigned • Comply with company policies, procedures, and applicable regulatory requirements

🎯 Requirements

• B.S. in Computer Science or related field required • 10+ years of professional software engineering experience, including significant experience in large-scale or complex systems • Expert-level proficiency with C# and .NET, including .NET Core / .NET 6+ • Extensive experience architecting and building React + TypeScript applications • Deep expertise with relational databases such as MS SQL Server, PostgreSQL, or MySQL, including schema design, performance tuning, and data modeling • Proven experience designing, implementing, and governing RESTful APIs and distributed systems • Strong background in software architecture, system design, and engineering best practices • Demonstrated experience leading technical initiatives, mentoring engineers, and influencing cross-functional decision-making • Strong understanding of DevOps principles, CI/CD pipelines, and cloud-native architectures • Excellent analytical and problem-solving skills with the ability to navigate ambiguity and complexity • Equivalent combination of education and experience may be considered • Experience in healthcare, clinical diagnostics, genomics, or NGS environments preferred • Familiarity with laboratory workflows, LIMS systems, or clinical reporting platforms preferred • Experience working in regulated environments such as CLIA, CAP, or HIPAA preferred • Background in designing secure, compliant, and audit-ready systems preferred • Experience with high-performance or data-intensive applications, including optimization and scalability strategies preferred

🏖️ Benefits

• Remote work arrangement • Equal opportunity and inclusive workplace • Reasonable accommodation during the application process