Vice President, Supply Chain

Job not on LinkedIn

🔥 0 minutes ago

🇺🇸 United States – Remote

💵 $300k - $340k / year

⏰ Full Time

🔴 Lead

🔗 Supply Chain

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Enliven Therapeutics

WebsiteLinkedInAll Job Openings

11 - 50 employees

🏥 Healthcare

💼 Consulting

🧬 Biotechnology

Healthcare • Consulting • Biotechnology

Enliven Therapeutics is a company dedicated to developing innovative solutions for cancer treatment. They focus on creating small molecule kinase inhibitors designed to improve efficacy, safety, and patient convenience. With programs targeting BCR-ABL, HER2, and additional pathways, Enliven Therapeutics aims to enhance the precision and selectivity of cancer therapeutics, combat resistance, and address brain metastases. The company prides itself on a team of experienced drug developers and aims to help cancer patients live longer and better lives.

📋 Description

• Own Enliven’s global supply chain strategy while preparing the company for late-stage development, regulatory approval, and commercial supply • Ensure uninterrupted supply of investigational product across Enliven’s clinical programs • Coordinate with CMC, Clinical Operations, Quality, Regulatory, Commercial, Finance, Legal, and other functions • Translate clinical protocols, enrollment assumptions, development plans, and manufacturing schedules into demand forecasts, supply plans, inventory strategies, and budgets • Oversee forecasting, production planning, packaging, labeling, distribution, inventory management, logistics, returns, reconciliation, and destruction • Oversee global logistics, import/export activities, customs documentation, depot strategy, and country-specific labeling and distribution requirements • Establish inventory and safety-stock strategies • Identify supply gaps, capacity constraints, and logistics challenges; develop contingencies and mitigation plans • Lead resolution of supply disruptions and unplanned events affecting clinical timelines or patient supply • Oversee IRT-related supply strategy and comparator sourcing • Support clinical and regulatory documentation, submissions, inspections, and audit-readiness activities • Develop and execute the transition roadmap from clinical-stage supply to scalable commercial supply • Establish processes, systems, governance, and external partnerships for late-stage development, launch, and commercial supply • Lead commercial supply and launch-readiness planning, including demand and supply planning, serialization, distribution, logistics, 3PL strategy, and product traceability • Partner with Commercial and Finance on integrated forecasting, demand planning, and S&OP/IBP capabilities • Develop launch scenarios and contingency plans • Oversee CMOs/CDMOs, packaging and labeling providers, depots, logistics providers, and 3PLs • Lead vendor evaluation, selection, contracting, onboarding, governance, and performance management, including RFPs and SOWs • Develop sourcing, contracting, capacity-planning, and business-continuity strategies • Maintain visibility into inventory, supply status, risks, budgets, and key decisions; provide updates to senior leadership • Develop scalable SOPs, planning processes, systems, and performance metrics • Serve as supply-chain subject-matter expert during audits and inspections • Represent Supply Chain or CMC/Technical Operations in program teams, governance forums, and leadership discussions • Communicate supply strategy, readiness, risks, tradeoffs, and investment requirements to executive leadership • Provide direction and support to supply-chain team members

🎯 Requirements

• Required Bachelor’s degree in supply chain, engineering, life sciences, business, or a related field; advanced degree preferred • Approximately 15 or more years of progressively responsible pharmaceutical or biotechnology supply-chain experience • Deep, hands-on experience leading global clinical supply, including forecasting, inventory management, packaging and labeling, distribution, logistics, and external-partner oversight • Experience leading supply chain for pivotal/Phase 3 clinical development and transitioning products from clinical-stage operations through commercial readiness • Firsthand experience establishing commercial supply-chain capabilities and playing a supply chain leadership role in at least one pharmaceutical product launch, including supporting NDA readiness and pre-approval inspections • Strong knowledge of clinical and commercial supply requirements, including demand planning, inventory strategy, packaging and labeling, serialization, distribution, 3PL management, and product traceability • Experience managing CMOs/CDMOs and other outsourced supply partners within a virtual or highly outsourced biotechnology model • Experience building and leading supply chain organizations, including planning internal staffing, consultant support and outsourced capabilities • Strong understanding of GMP, GDP, and applicable global clinical-supply requirements • Experience leading or materially participating in ERP/planning/inventory management/supply visibility systems implementation • Demonstrated ability to anticipate supply gaps, build practical contingency plans, and resolve disruptions quickly • Ability to work effectively at both strategic and tactical levels in a small or mid-sized biotechnology company • Strong cross-functional leadership, communication, financial judgment, negotiation, and problem-solving skills • Ability to manage multiple priorities and make sound decisions in a fast-paced, evolving environment • Preferred experience building clinical and commercial supply capabilities for an emerging biotechnology company’s first commercial product • Experience with small-molecule pharmaceutical products and outsourced global manufacturing and distribution networks • Experience supporting global, multi-region clinical trials • Experience supporting U.S. and international product launches • Working knowledge of IRT systems • Background screen required as a condition of employment

🏖️ Benefits

• Bonus may be provided • Equity may be provided • Occasional evening, weekend, holiday, and on-call work may be required as job duties demand • Approximately 15% travel may be expected • Equal opportunity employer