Director, Global Value, Health Economics and Outcomes Research

🔥 2 minutes ago

🌐 United States, United Kingdom – Remote

🇺🇸 United States – Remote 🇬🇧 United Kingdom – Remote

🏄 California, Pennsylvania – Remote

🏄 California – Remote 🔔 Pennsylvania – Remote

💵 $212k - $318k / year

⏰ Full Time

🔴 Lead

👔 Director

🦅 H1B Visa Sponsor

This company has sponsored H1B visas in the past.

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Jazz Pharmaceuticals

WebsiteLinkedInAll Job Openings

1001 - 5000 employees

Founded 2003

🏥 Healthcare

🏭 Manufacturing

🧬 Biotechnology

Healthcare • Manufacturing • Biotechnology

Jazz Pharmaceuticals is a biopharmaceutical company dedicated to developing innovative medicines that address serious unmet medical needs. With a strong commitment to research and development, Jazz focuses on creating life-changing therapies, emphasizing the importance of collaboration, diversity, and employee engagement in its operations. The company prides itself on transforming patients' lives through its meaningful product offerings and a culture that fosters enthusiasm and flexibility.

📋 Description

• Define and drive global and US payer evidence strategy for pipeline assets from Phase 2/3 through regulatory approval and launch • Lead global payer evidence generation while serving as the US HEOR lead • Develop US pre-launch HEOR deliverables, payer field enablement tools, and US market access evidence strategies • Translate target product profiles and access ambitions into evidence generation programs • Partner with Clinical Development, Biostatistics, and Clinical Operations to integrate payer, formulary, and HTA requirements into Phase 2/3 trial designs • Optimize trial protocols, comparators, inclusion/exclusion criteria, treatment lines, and endpoints • Integrate PROs, HRQoL, symptom burden scales, and HCRU instruments into pivotal trials • Design evidence strategies for rare disease assets using natural history data, biomarkers, and external or historical comparator cohorts • Lead health economic modeling strategies, including conceptual models, threshold analyses, CEAs, and BIMs • Direct design, development, and validation of adaptable global core economic models • Lead US AMCP PIE dossiers, burden-of-illness dossiers, and US budget impact models • Design payer-facing economic models, evidence slide decks, and population health tools • Support ICER evaluations, IRA planning, and CMS price negotiation readiness • Lead HEOR workstreams within Launch Readiness Teams and oversee global launch evidence assets • Co-develop EU/INT HTA strategies and analytical packages for JCA, NICE, G-BA, CADTH, and other bodies • Design and execute pre-launch real-world studies, chart reviews, registries, and burden-of-illness evaluations • Govern the Integrated Evidence Generation Plan and coordinate cross-functional evidence priorities • Develop scientific publication plans, manuscripts, and congress presentations • Mentor junior HEOR scientists, post-doctoral fellows, and matrix colleagues

🎯 Requirements

• Master’s degree (MSc, MS, MPH, PhD) in Health Economics, Outcomes Research, Pharmacoeconomics, or a closely related quantitative field • Minimum of 7–10 years of experience in HEOR, Global Value, or Health Economics within the biopharmaceutical industry or a top-tier HEOR consulting firm • Experience with neurology assets preferred • Direct experience leading HEOR strategy and deliverables for pipeline assets, including early Phase 2/3 clinical trial protocol integration, endpoint development, and global launch readiness • Experience managing regional trade offs on evidence needs as part of Phase 2/3 protocol development • Launch lead for at least 2 assets as US HEOR lead, or country level HTA lead • Proven track record serving as the US HEOR lead or driving US pre-launch HEOR deliverables • Preferred direct experience in rare disease, orphan drug, or highly specialized pipeline programs • Demonstrated hands-on experience designing, overseeing, or adapting health economic models • Demonstrated track record collaborating with regional HEOR teams • Deep expertise in health economic modeling, including Markov state-transition, partitioned survival, microsimulation, and decision-tree models • Familiarity with US managed care and market access, Medicare Advantage, Medicare Part D/B, Medicaid, PBMs, and global HTA frameworks • Experience with GVDs, AMCP PIE dossiers, global ITCs/NMAs, US budget impact models, natural history studies, registries, external control arms, and specialized HTA pathways • Exceptional written and verbal communication skills, with an established record of HEOR and clinical publications or HTA success

🏖️ Benefits

• Discretionary annual cash bonus or incentive compensation • Discretionary equity grants • Medical insurance • Dental insurance • Vision insurance • 401k retirement savings plan • Flexible paid vacation

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