Lead Bioinformatics Scientist – Sample to Answer

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🏄 California – Remote

🏄 California – Remote

💵 $120k - $150k / year

⏰ Full Time

🟠 Senior

👻 Ghost score 0%

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Labcorp

WebsiteLinkedInAll Job Openings

10,000+ employees

🏥 Healthcare

💊 Pharmaceuticals

🧬 Biotechnology

💰 $2G Post-IPO Debt - LabCorp on 2024-09

Healthcare • Pharmaceuticals • Biotechnology

Labcorp is a global leader in laboratory services, diagnostics, and drug development. The company provides testing, data and scientific insights to doctors, hospitals, pharmaceutical companies, researchers and patients, reaching more than 160 million patients annually. Labcorp operates a large global laboratory footprint with roughly 71,000 employees across 100+ countries and invests in advanced technologies (including AI and digital solutions) to accelerate drug development, support precision medicines (such as cell and gene therapies and oncology diagnostics), and inform clinical decision-making.

📋 Description

• Produce innovative solutions through exploratory data analysis of complex, high-dimensional datasets • Apply statistics, data modeling, data science, and artificial intelligence to recognize patterns and identify opportunities • Design, develop, and evaluate predictive models for single-gene non-invasive fetal screening (NIFS) • Generate and test hypotheses from ideation through delivery • Collaborate with R&D scientists to develop new assays, measurement technologies, and tests for clinical conditions • Analyze genomic, transcriptomic, and proteomic datasets using bioinformatics tools and NGS pipelines • Perform statistical and bioinformatics analyses of experimental data from DNA sequencers and other molecular instruments • Conduct data mining across internally produced and publicly available datasets • Provide analysis information to management for new laboratory-developed test decisions • Develop statistical classifiers and decision trees using read support, flanking-read ratios, allele dropout indicators, and confidence intervals • Apply bioinformatics algorithms and develop novel computational approaches • Investigate molecular-level assay limitations and define clinical reporting boundaries • Develop and optimize complex bioinformatics analysis pipelines • Architect production-grade Nextflow whole-genome sequencing pipelines, including caller selection, annotation strategy, and QC threshold design • Lead bioinformatics proof-of-concepts for sequencer transitions, including concordance analysis, metric comparison, GIAB benchmarking, and cost-benefit recommendations • Improve accuracy, cost of goods sold (COGS), and turnaround time across the pipeline portfolio • Establish quality-control metrics and procedures for production pipeline data integrity • Guide result interpretation and reporting standards with clinical and commercial stakeholders • Set QC thresholds for new sample metrics and make production-impacting recommendations

🎯 Requirements

• Ph.D. in bioinformatics, computational biology, genetics, or computer science • 3 or more years of experience in biotechnology • 5 or more years of experience in programming languages in bioinformatics, such as Python, R, Perl, or Java • 5 or more years of experience with high-throughput sequencing data and bioinformatics tools like BLAST, GATK, or Bowtie (preferred) • 5 or more years of experience with Linux/Unix environments and high-performance computing (HPC) or cloud platforms (preferred) • Ability to effectively provide guidance to junior team members • Success in technical proficiency, scientific creativity, collaboration with others, and independent thought • Evidence of relevant research expertise through presentations, software, technical publications, and knowledge of applications • Proficiency in data analysis and statistical learning • Ability to exercise independent judgment in developing methods, techniques, and evaluation criteria • US-based work location

🏖️ Benefits

• Annual bonus under the Labcorp Bonus Plan • Medical benefits • Dental benefits • Vision benefits • Life insurance • Short-term disability (STD) • Long-term disability (LTD) • 401(k) • Paid Time Off (PTO) or Flexible Time Off (FTO) • Tuition Reimbursement • Employee Stock Purchase Plan