Lead Bioinformatics Scientist – Sample to Answer

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🏄 California – Remote

🏄 California – Remote

💵 $120k - $150k / year

⏰ Full Time

🟠 Senior

🦅 H1B Visa Sponsor

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Labcorp

WebsiteLinkedInAll Job Openings

10,000+ employees

Founded 1969

💼 Consulting

📦 Logistics

🏥 Healthcare

💰 Post-IPO Debt on 2019-06

Consulting • Logistics • Healthcare

Labcorp is a leading global life sciences company that provides comprehensive clinical laboratory and end-to-end drug development services. The company offers a wide range of diagnostic tests and services for patients, providers, and biopharmaceutical companies. Labcorp specializes in areas such as oncology, women's health, neurology, and genetics, offering both routine and specialized laboratory testing. It supports healthcare systems and organizations with clinical lab testing, health assessments, and employee wellness programs. Labcorp also plays a significant role in the biopharma sector, providing nonclinical research, central laboratory services, and consulting for drug development and commercialization. With their commitment to science and innovation, Labcorp aims to improve health and change lives worldwide.

📋 Description

• Produce innovative solutions through exploratory data analysis of complex, high-dimensional datasets • Apply statistics, data modeling, data science, and artificial intelligence to identify patterns and opportunities • Design, develop, and evaluate predictive models for single-gene non-invasive Fetal Screening (NIFS) • Generate and test hypotheses from ideation through delivery • Collaborate with R&D scientists to develop new assays, measurement technologies, and clinical tests • Analyze genomic, transcriptomic, and proteomic datasets using bioinformatics tools and NGS pipelines • Perform statistical and bioinformatics analyses of experimental data from DNA sequencers and molecular instruments • Mine internally produced and publicly available datasets • Provide analysis information to management for decisions on new laboratory developed tests • Develop statistical classifiers and decision trees using genomic read-support and allele-dropout metrics • Apply bioinformatics algorithms and develop novel computational approaches • Investigate molecular-level assay limitations and define clinical reporting boundaries • Develop and optimize complex bioinformatics analysis pipelines • Architect production-grade Nextflow whole-genome sequencing pipelines, including caller selection, annotation strategy, and QC threshold design • Lead bioinformatics proofs of concept for sequencer transitions, including concordance analysis, metric comparison, GIAB benchmarking, and cost-benefit recommendations • Improve pipeline accuracy, cost of goods sold, and turnaround time • Establish quality-control metrics and procedures for production pipelines • Guide result interpretation and reporting standards with clinical and commercial stakeholders • Set QC thresholds for new sample metrics and make production-impacting recommendations

🎯 Requirements

• Ph.D. in bioinformatics, computational biology, genetics, or computer science • 3 or more years of experience in biotechnology • 5 or more years of experience in programming languages in bioinformatics, such as Python, R, Perl, or Java • 5 or more years of experience with high-throughput sequencing data and bioinformatics tools like BLAST, GATK, or Bowtie • 5 or more years of experience with Linux/Unix environments and high-performance computing (HPC) or cloud platforms • Ability to effectively provide guidance to junior team members • Demonstrated success in technical proficiency, scientific creativity, collaboration with others and independent thought • Evidence of relevant research expertise through presentations, software, technical publications, and knowledge of applications • Proficiency in data analysis and statistical learning • Ability to exercise independent judgment in developing methods, techniques and evaluation criteria for obtaining results

🏖️ Benefits

• Annual bonus under the Labcorp Bonus Plan • Medical insurance • Dental insurance • Vision insurance • Life insurance • Short-term disability (STD) • Long-term disability (LTD) • 401(k) • Paid Time Off (PTO) or Flexible Time Off (FTO) • Tuition Reimbursement • Employee Stock Purchase Plan