AI Biologist – Structural Biology

Job not on LinkedIn

🔥 5 minutes ago

🏄 California – Remote

🏄 California – Remote

💵 $120k - $180k / year

⏰ Full Time

🟡 Mid-level

🟠 Senior

🤖 Artificial Intelligence

👻 Ghost score 8%

What it means: how likely this posting is sitting open without active hiring.How to read it: 60% or higher means we think this is a ghost. Lower scores are less of a worry.How we score it: age, reposts, open roles vs team size, how fast jobs close, and whether pay is listed.Fine print: an estimate from public data, not a judgment of the company. Real jobs can score high, so treat it as a hint, not a fact.

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LatchBio

WebsiteLinkedInAll Job Openings

11 - 50 employees

Founded 2021

🧬 Biotechnology

🤖 Artificial Intelligence

☁️ SaaS

💰 $28M Series A - LatchBio on 2022-06

Biotechnology • Artificial Intelligence • SaaS

LatchBio is a biotech-focused software and AI company that builds a modular, enterprise-grade platform to analyze and operationalize complex biological data and deploy frontier AI agents into real scientific workflows. It produces reproducible, Nextflow-based workflows, scalable compute “pods,” file and metadata registries, and white‑labeled analysis portals for solution providers and biopharma/R&D labs. In parallel, LatchBio develops and publishes verifiable benchmarks that evaluate how modern AI agents perform on real-world biological tasks (single‑cell, spatial, epigenomics, preclinical pharmacology, and pathogen genomic surveillance), and has expanded into biosecurity work through the acquisition of TwentyTwo and the formation of Latch Biosecurity. The company’s customers include instrument vendors, biopharma, and academic research organizations.

📋 Description

• Define expert reasoning and write gold-standard answers for structural biology questions • Design realistic scenarios across data collection, processing, map interpretation, model building, validation, assembly, state assignment, comparison, functional interpretation, interaction analysis, molecular dynamics, and metadynamics • Curate datasets spanning X-ray, cryo-EM, atomic models, AlphaFold, molecular dynamics, NMR, SAXS, HDX-MS, cross-linking, and SHAPE/DMS modalities • Build Python analysis pipelines using gemmi, Biopython/biotite, and numpy • Partner with software engineers to create benchmark workflows • Test agents for artifacts, over-interpretation, incorrect interfaces, register shifts, mirrored maps, misdocked domains, and misuse of B-factors or occupancies • Adjudicate ambiguous structural cases and identify evidence needed to resolve them • Evaluate representations and comparisons, including biological assemblies, asymmetric units, reference states, and domain superposition • Interrogate agent reasoning and challenge scientifically unsound conclusions • Identify agent errors and explain expert alternatives • Score agent confidence and reward appropriate uncertainty

🎯 Requirements

• PhD in structural biology, biophysics, biochemistry, or a related field • Hands-on structural experience building and validating models • Deep expertise in at least one area: X-ray crystallography, cryo-EM, NMR/solution methods, or computational structural biology • Working fluency across the other structural biology methods • Ability to compute contacts, superpositions, symmetry mates, map values, and geometry from files without a GUI • Coding experience for structural data • Daily use of Claude, Cursor, or similar AI agents • Judgment to identify scientifically unsound AI reasoning • Ability to calibrate confidence and communicate uncertainty • US citizenship, permanent residency, or OPT-holder status • No STEM OPT extension or sponsorship support

🏖️ Benefits

• Guaranteed pay for weeks 1–4 while ramping • Uncapped upside • Full-time work on your own schedule • Catered lunch and dinner daily for onsite employees • Waterfront office in Mission Bay • Monthly parking when available • Company outings most months • Team off-sites • Latch run club, cycling, boxing, ice skating, and soccer • Opportunity to move across teams • Potential for rapid advancement into senior roles